Evidence map›Paper›PMID 30546257›Full record

ReviewBioinformatics and biology insights2018

Genomic Interventions in Medicine.

Oluwadurotimi S Aworunse, Oluwatomiwa Adeniji, Olusola L Oyesola, Itunuoluwa Isewon, Jelili Oyelade, Olawole O Obembe

Abstract readReview
In one paragraph

Review in Bioinformatics and biology insights, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Oluwadurotimi S AworunseDepartment of Biological Sciences, Covenant University, Ota, Nigeria.
Oluwatomiwa AdenijiDepartment of Biological Sciences, Covenant University, Ota, Nigeria.
Olusola L OyesolaDepartment of Biological Sciences, Covenant University, Ota, Nigeria.
Itunuoluwa IsewonDepartment of Computer & Information Sciences, Covenant University, Ota, Nigeria.
Jelili OyeladeDepartment of Computer & Information Sciences, Covenant University, Ota, Nigeria.ORCID https://orcid.org/0000-0002-5476-4992
Olawole O ObembeDepartment of Biological Sciences, Covenant University, Ota, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lately, the term "genomics" has become ubiquitous in many scientific articles. It is a rapidly growing aspect of the biomedical sciences that studies the genome. The human genome contains a torrent of information that gives clues about human origin, evolution, biological function, and diseases. In a bid to demystify the workings of the genome, the Human Genome Project (HGP) was initiated in 1990, with the chief goal of sequencing the approximately 3 billion nucleotide base pairs of the human DNA. Since its completion in 2003, the HGP has opened new avenues for the application of genomics in clinical practice. This review attempts to overview some milestone discoveries that paved way for the initiation of the HGP, remarkable revelations from the HGP, and how genomics is influencing a paradigm shift in routine clinical practice. It further highlights the challenges facing the implementation of genomic medicine, particularly in Africa. Possible solutions are also discussed.

Indexed as

diagnosisgene therapyGenomicsHuman Genome Projectpersonalized medicinepharmacogenomics

Identifiers

PMID30546257
PMCPMC6287307

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.