Evidence map›Paper›PMID 30546250›Full record

ArticleThe Egyptian journal of neurology, psychiatry and neurosurgery2018

Investigating the influence of ubiquinone blood level on the abilities of children with specific learning disorder.

Ehab Ragaa Abdelraouf, Ayman Kilany, Adel F Hashish, Ola Hosny Gebril, Suzette Ibrahim Helal, Haytham Mohamad Hasan, Neveen Hassan Nashaat

Open access · diamondAbstract read
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In one paragraph

Article in The Egyptian journal of neurology, psychiatry and neurosurgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Increased Agmatine Degradation in Children with Specific Learning Disorder.International journal of molecular sciences · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ehab Ragaa Abdelraouf1Research on Children with Special Needs Department, Medical Research division, National Research Centre, Elbuhouth Street, 12622, Dokki, Cairo, Egypt.
Ayman Kilany1Research on Children with Special Needs Department, Medical Research division, National Research Centre, Elbuhouth Street, 12622, Dokki, Cairo, Egypt.
Adel F Hashish1Research on Children with Special Needs Department, Medical Research division, National Research Centre, Elbuhouth Street, 12622, Dokki, Cairo, Egypt.
Ola Hosny Gebril1Research on Children with Special Needs Department, Medical Research division, National Research Centre, Elbuhouth Street, 12622, Dokki, Cairo, Egypt.
Suzette Ibrahim Helal1Research on Children with Special Needs Department, Medical Research division, National Research Centre, Elbuhouth Street, 12622, Dokki, Cairo, Egypt.
Haytham Mohamad Hasan1Research on Children with Special Needs Department, Medical Research division, National Research Centre, Elbuhouth Street, 12622, Dokki, Cairo, Egypt.
Neveen Hassan Nashaat1Research on Children with Special Needs Department, Medical Research division, National Research Centre, Elbuhouth Street, 12622, Dokki, Cairo, Egypt.ORCID 0000-0003-1553-9327
National Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUbiquinone has antioxidant properties and has been linked to cognitive performance in some neuropsychiatric disorders. Its role in specific learning disorder manifestations has not been previously investigated. Therefore, the aim of this study was to measure the blood levels of ubiquinone in a group of children with specific learning disorder in comparison to typically developing children and to investigate the correlation between ubiquinone levels in children with specific learning disorder and some of their intellectual capabilities, reading, spelling and writing performance.

methodsThe study included 71 native Arabic speaking children: 31 in the specific learning disorder group and 40 in the typically developing (TD) group. The abilities of the children with specific learning disorder were evaluated by the Stanford-Binet Intelligence Scale-4th edition, the Dyslexia Assessment Test, and the Illinois Test of Psycholinguistic Abilities. The level of ubiquinone was measured in both groups by ELISA. Correlation between some aptitudes of children with specific learning disorder and the ubiquinone level was performed.

resultsThe blood levels of ubiquinone in the children with specific learning disorder group were less than those in the TD group. Correlation analysis revealed a significant positive correlation between ubiquinone and the scores of backward digit span abilities.

conclusionsUbiquinone has a role in the auditory working memory performance of children with specific learning disorder (with impairment in reading). The decreased levels of ubiquinone in this sample of children with specific learning disorder could have participated in the pathogenesis of this disorder.

Indexed as

CorrelationMemorySpecific learning disorderUbiquinone level

Identifiers

PMID30546250
PMCPMC6267631
OpenAlexW2903031888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.