Evidence map›Paper›PMID 30546044›Full record

ArticleScientific reports2018

Quantitative Model for Ion Transport and Cytoplasm Conductivity of Chinese Hamster Ovary Cells.

Azita Fazelkhah, Katrin Braasch, Samaneh Afshar, Elham Salimi, Michael Butler, Greg Bridges, Douglas Thomson

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Azita FazelkhahDepartment of Electrical and Computer Engineering, University of Manitoba, Winnipeg, R3T 2N2, Canada.ORCID http://orcid.org/0000-0002-6520-5002
Katrin BraaschDepartment of Microbiology, University of Manitoba, Winnipeg, R3T 2N2, Canada.
Samaneh AfsharDepartment of Electrical and Computer Engineering, University of Manitoba, Winnipeg, R3T 2N2, Canada.
Elham SalimiDepartment of Electrical and Computer Engineering, University of Manitoba, Winnipeg, R3T 2N2, Canada.
Michael ButlerNational Institute for Bioprocessing Research and Training, Dublin, Ireland.
Greg BridgesDepartment of Electrical and Computer Engineering, University of Manitoba, Winnipeg, R3T 2N2, Canada.
Douglas ThomsonDepartment of Electrical and Computer Engineering, University of Manitoba, Winnipeg, R3T 2N2, Canada. Douglas.thomson@umanitoba.ca.
University of Manitoba · CANational Institute for Bioprocessing Research and Training · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In mammalian cells cytoplasm ion concentrations and hence cytoplasm conductivity is an important indicator of their physiological state. Changes in the cytoplasm conductivity has been associated with physiological changes such as progression of cancer and apoptosis. In this work, a model that predicts the effects of physiological changes in ion transport on the cytoplasm conductivity of Chinese hamster ovary (CHO) cells is demonstrated. We determined CHO-specific model parameters, Na

Indexed as

Models, BiologicalAnimalsCHO CellsCricetinaeCricetulusCytoplasmIon TransportOuabainSodium-Potassium-Exchanging ATPaseOuabainSodium-Potassium-Exchanging ATPase

Identifiers

PMID30546044
PMCPMC6292909
OpenAlexW2903832997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.