ReviewThe European respiratory journal2019
Intensive care, right ventricular support and lung transplantation in patients with pulmonary hypertension.
Review in The European respiratory journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 1 synthesis or guideline pooled it, 209 citations in OpenAlex.
- Pooled it
- Mechanisms and Advances in the Treatment of Arrhythmias Associated With Pulmonary Hypertension.Reviews in cardiovascular medicine · 2026Review
- Heart-lung transplantation in the United Kingdom: Trends and outcomes over 4 decades.JHLT open · 2026Article
- Article
- Pressure-flow discordance in perioperative pulmonary hypertension: a mechanism-based review and provisional five-domain right-heart model for noncardiac surgery.Frontiers in medicine · 2026Review
- Diuretic adherence in patients with pre-capillary pulmonary hypertension: insights from the PHARE study.ERJ open research · 2025Article
- Evaluation and Management of Sepsis in Pulmonary Hypertension.Journal of intensive care medicine · 2025Review
- Extended Use of Central Veno-Arterial Extracorporeal Membrane Oxygenation in Lung Transplantation for Patients with Pulmonary Arterial Hypertension.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025Article
- Early Extracorporeal Membrane Oxygenation Initiation May Improve Outcomes in Select Patients With Primary Pulmonary Hypertension: An Extracorporeal Life Support Organization Registry Analysis.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2025Article
- Observational
- Timing of lung transplant evaluation: considerations, barriers and alternatives.Current opinion in pulmonary medicine · 2025Review
- Phase 2 Study to Evaluate the Efficacy and Safety of Inhaled Nitric Oxide Therapy in Patients With Severe Right Heart Failure Associated With Pulmonary Hypertension - Protocol for the PHiNO Study.Circulation reports · 2025Article
- Approach to Lung Transplantation in Pulmonary Arterial Hypertension: A Delphi Consensus on Behalf of the Transplant Task Force of the Pulmonary Vascular Research Institute.Pulmonary circulation · 2025Article
- Fluid balance and clinical outcomes in patients with aortic dissection: a retrospective case-control study based on ICU databases.BMJ open · 2025Article
- Mechanisms and treatment of pulmonary arterial hypertension.Nature reviews. Cardiology · 2025Review
- The role of extracorporeal membrane oxygenation in thoracic anesthesia.Current opinion in anaesthesiology · 2025Review
- Impact of Pulmonary Hypertension on Posttransplant Survival of Patients With Pulmonary Fibrosis at High Altitude: A Prospective Cohort Study.Canadian respiratory journal · 2025Article
- Transplantation, bridging, and support technologies in pulmonary hypertension.The European respiratory journal · 2024Review
- Case report: Extracorporeal life support as a successful bridge to recovery in an incident case of pulmonary arterial hypertension.Frontiers in medicine · 2024Article
- Outcomes of Lung Transplantation in Patients With Right Ventricular Dysfunction: A Single-Center Retrospective Analysis Comparing ECMO Configurations in a Bridge-to-Transplant Setting.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 7 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intensive care of patients with pulmonary hypertension (PH) and right-sided heart failure includes treatment of factors causing or contributing to heart failure, careful fluid management, and strategies to reduce ventricular afterload and improve cardiac function. Extracorporeal membrane oxygenation (ECMO) should be considered in distinct situations, especially in candidates for lung transplantation (bridge to transplant) or, occasionally, in patients with a reversible cause of right-sided heart failure (bridge to recovery). ECMO should not be used in patients with end-stage disease without a realistic chance for recovery or for transplantation. For patients with refractory disease, lung transplantation remains an important treatment option. Patients should be referred to a transplant centre when they remain in an intermediate- or high-risk category despite receiving optimised pulmonary arterial hypertension therapy. Meticulous peri-operative management including the intra-operative and post-operative use of ECMO effectively prevents graft failure. In experienced centres, the 1-year survival rates after lung transplantation for PH now exceed 90%.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.