Evidence map›Paper›PMID 30545969›Full record

ReviewThe European respiratory journal2019

Chronic thromboembolic pulmonary hypertension.

Nick H Kim, Marion Delcroix, Xavier Jais, Michael M Madani, Hiromi Matsubara, Eckhard Mayer, Takeshi Ogo, Victor F Tapson, Hossein-Ardeschir Ghofrani, David P Jenkins

Abstract readReview
In one paragraph

Review in The European respiratory journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 343 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
343citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

343 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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283 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nick H KimDept of Medicine, University of California San Diego, La Jolla, CA, USA.
Marion DelcroixDept of Respiratory Diseases, University Hospitals of Leuven and Respiratory Division, Dept CHROMETA, KU Leuven - University of Leuven, Leuven, Belgium.ORCID 0000-0001-8394-9809
Xavier JaisUniversité Paris-Sud, AP-HP, Centre de Référence de l'Hypertension Pulmonaire, Service de Pneumologie, Département Hospitalo-Universitaire (DHU) Thorax Innovation (TORINO), Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Michael M MadaniCardiovascular and Thoracic Surgery, University of California San Diego, La Jolla, CA, USA.
Hiromi MatsubaraNational Hospital Organization Okayama Medical Center, Okayama, Japan.
Eckhard MayerKerckhoff Clinic Bad Nauheim, University of Giessen, Bad Nauheim, Germany.
Takeshi OgoDivision of Advanced Medical Research in Pulmonary Hypertension, Dept of Pulmonary Circulation, National Cerebral and Cardiovascular Center, Osaka, Japan.
Victor F TapsonDept of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Hossein-Ardeschir GhofraniKerckhoff Clinic Bad Nauheim, University of Giessen, Bad Nauheim, Germany.ORCID 0000-0002-2029-4419
David P JenkinsRoyal Papworth Hospital, Cambridge, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) is a complication of pulmonary embolism and a major cause of chronic PH leading to right heart failure and death. Lung ventilation/perfusion scintigraphy is the screening test of choice; a normal scan rules out CTEPH. In the case of an abnormal perfusion scan, a high-quality pulmonary angiogram is necessary to confirm and define the pulmonary vascular involvement and prior to making a treatment decision. PH is confirmed with right heart catheterisation, which is also necessary for treatment determination. In addition to chronic anticoagulation therapy, each patient with CTEPH should receive treatment assessment starting with evaluation for pulmonary endarterectomy, which is the guideline recommended treatment. For technically inoperable cases, PH-targeted medical therapy is recommended (currently riociguat based on the CHEST studies), and balloon pulmonary angioplasty should be considered at a centre experienced with this challenging but potentially effective and complementary intervention.

Indexed as

AngiographyAngioplasty, BalloonAnticoagulantsCardiac CatheterizationChronic DiseaseEndarterectomyHeart FailureHumansHypertension, PulmonaryPulmonary EmbolismPyrazolesPyrimidinesTomography, X-Ray ComputedAnticoagulantsPyrazolesPyrimidinesriociguat

Identifiers

PMID30545969
PMCPMC6351341

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.