Evidence map›Paper›PMID 30545902›Full record

ArticleThe Journal of experimental medicine2019

Hierarchical assembly and disassembly of a transcriptionally active RAG locus in CD4

Abani Kanta Naik, Aaron T Byrd, Aaron C K Lucander, Michael S Krangel

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  4. Article
  5. The Function of E2A in B-Cell Development.Advances in experimental medicine and biology · 2024
    Review
  6. Article
  7. IKAROS in Acute Leukemia: A Positive Influencer or a Mean Hater?International journal of molecular sciences · 2023
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Abani Kanta NaikDepartment of Immunology, Duke University Medical Center, Durham, NC.
Aaron T ByrdDepartment of Immunology, Duke University Medical Center, Durham, NC.
Aaron C K LucanderDepartment of Immunology, Duke University Medical Center, Durham, NC.ORCID 0000-0002-1292-2147
Michael S KrangelDepartment of Immunology, Duke University Medical Center, Durham, NC krang001@mc.duke.edu.ORCID 0000-0003-1292-254X
Duke Medical Center · US

Funding

Control Of Tcr Delta And Tcr Alpha RearrangementR37GM041052 · NIGMS · DUKE UNIVERSITY · PI KRANGEL, MICHAEL S · 2006 to 2015
$5.1M
HUMAN GAMMA DELTA T CELL RECEPTORR01GM041052 · NIGMS · DUKE UNIVERSITY · PI KRANGEL, MICHAEL S · 1989 to 2019
$4.8M
Data commons for 'omic, microscopy and analysis core facilitiesS10OD018164 · OD · DUKE UNIVERSITY · PI WRAY, GREGORY A. · 2014 to 2014
$598k
NIGMS NIH HHS R01 GM041052NIGMS NIH HHS R37 GM041052NIH HHS S10 OD018164
6 · The paper itself

Abstract

Expression of

Indexed as

AnimalsBasic Helix-Loop-Helix ProteinsCD4 AntigensCD8 AntigensDNA-Binding ProteinsGATA3 Transcription FactorGene Expression RegulationGenetic LociHomeodomain ProteinsIkaros Transcription FactorMiceResponse ElementsThymocytesTranscription, GeneticBasic Helix-Loop-Helix ProteinsCD4 AntigensCD8 antigen, alpha chainCD8 AntigensDNA-Binding ProteinsGata3 protein, mouseGATA3 Transcription FactorHomeodomain ProteinsIkaros Transcription FactorRAG-1 proteinRag2 protein, mouseTcf3 protein, mouseZfpn1a1 protein, mouse

Identifiers

PMID30545902
PMCPMC6314527
OpenAlexW2904350263

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.