Evidence map›Paper›PMID 30545682›Full record

ArticleAcademic radiology2019

Calibrated Breast Density Measurements.

Erin E Fowler, Autumn Smallwood, Nadia Khan, Cassandra Miltich, Jennifer Drukteinis, Thomas A Sellers, John Heine

Abstract read
In one paragraph

Article in Academic radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Breast Density Analysis Using Digital Breast Tomosynthesis.bioRxiv : the preprint server for biology · 2023
    Article
  2. Reporting breast density on chest computed tomography.Translational breast cancer research : a journal focusing on translational research in breast cancer · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Erin E FowlerCancer Epidemiology Department, Moffitt Cancer Center & Research Institute, 12902 Bruce B Downs Blvd, Mail Stop: MRC Can/Cont, Tampa, FL 33612.
Autumn SmallwoodCorporate Compliance Department, Moffitt Cancer Center & Research Institute, 12902 Bruce B Downs Blvd, Tampa, FL 33612.
Nadia KhanNo Affiliation.
Cassandra MiltichCancer Epidemiology Department, Moffitt Cancer Center & Research Institute, 12902 Bruce B Downs Blvd, Mail Stop: MRC Can/Cont, Tampa, FL 33612.
Jennifer DrukteinisNo Affiliation.
Thomas A SellersCancer Epidemiology Department, Moffitt Cancer Center & Research Institute, 12902 Bruce B Downs Blvd, Mail Stop: MRC Can/Cont, Tampa, FL 33612.
John HeineCancer Epidemiology Department, Moffitt Cancer Center & Research Institute, 12902 Bruce B Downs Blvd, Mail Stop: MRC Can/Cont, Tampa, FL 33612. Electronic address: john.heine@moffitt.org.

Funding

Quantitative Imaging Clinical Validation Center at Moffitt Cancer CenterU01CA200464 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI JOHN J HEINE, Matthew B. Schabath · 2016 to 2026
$9.2M
Automated Quantitative Measures of Breast DensityR01CA166269 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI HEINE, JOHN J · 2013 to 2016
$2.5M
NCI NIH HHS R01 CA166269NCI NIH HHS U01 CA200464
6 · The paper itself

Abstract

RATIONALE AND

objectivesMammographic density is an important risk factor for breast cancer, but translation to the clinic requires assurance that prior work based on mammography is applicable to current technologies. The purpose of this work is to evaluate whether a calibration methodology developed previously produces breast density metrics predictive of breast cancer risk when applied to a case-control study. MATERIALS AND

methodsA matched case control study (n = 319 pairs) was used to evaluate two calibrated measures of breast density. Two-dimensional mammograms were acquired from six Hologic mammography units: three conventional Selenia two-dimensional full-field digital mammography systems and three Dimensions digital breast tomosynthesis systems. We evaluated the capability of two calibrated breast density measures to quantify breast cancer risk: the mean (PG

resultsIn adjusted models, both PG

conclusionThe calibrated PG

Indexed as

Breast DensityMammographyAgedArea Under CurveBreast NeoplasmsCalibrationCase-Control StudiesFemaleHumansMiddle AgedOdds RatioRisk AssessmentROC Curvebreast cancer riskbreast densityCalibrationmammography

Identifiers

PMID30545682
PMCPMC6557684

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.