ArticleParasites & vectors2018
First report of natural Wolbachia infection in the malaria mosquito Anopheles arabiensis in Tanzania.
Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed, 59 citations in OpenAlex.
- Detection of supergroup B Wolbachia strains and their co-infection with Plasmodium falciparum in wild Anopheles funestus in southeastern Tanzania: implications for malaria control.Parasites & vectors · 2026Article
- The presence of the wAnD strain of Wolbachia is correlated with lower levels of Plasmodium sporozoites and a less diverse microbiome in wild Anopheles demeilloni mosquito cephalothoraxes.Gates open research · 2026Article
- Advancing Malaria Vector Control: Insights Into Mosquito Immunity and Genetic Strategies.TheScientificWorldJournal · 2026Review
- Investigation of bacterial microbiota variability in two allopatric populations of Nyssomyia umbratilis, susceptible and nonsusceptible to Leishmania (Viannia) guyanensis infection in the Amazon region.Parasites & vectors · 2025Article
- Article
- Stable introduction of Wolbachia wPip into invasive Anopheles stephensi for potential malaria control.PLoS neglected tropical diseases · 2024Article
- Diversity of Wolbachia infections in Sri Lankan mosquitoes with a new record of Wolbachia Supergroup B infecting Aedes aegypti vector populations.Scientific reports · 2024Article
- Wolbachia infection-responsive immune genes suppress Plasmodium falciparum infection in Anopheles stephensi.PLoS pathogens · 2024Article
- Article
- Updates on traditional methods for combating malaria and emergingFrontiers in cellular and infection microbiology · 2024Review
- Characterizing the Wolbachia infection in field-collected Culicidae mosquitoes from Hainan Province, China.Parasites & vectors · 2023Article
- SymbioticFrontiers in microbiology · 2023Review
- Wolbachia 16S rRNA haplotypes detected in wild Anopheles stephensi in eastern Ethiopia.Parasites & vectors · 2022Article
- Article
- Molecular phylogeny of heritable symbionts and microbiota diversity analysis in phlebotominae sand flies and Culex nigripalpus from Colombia.PLoS neglected tropical diseases · 2021Article
- Wolbachia cifB induces cytoplasmic incompatibility in the malaria mosquito vector.Nature microbiology · 2021Article
- Characterization of the virome associated with Haemagogus mosquitoes in Trinidad, West Indies.Scientific reports · 2021Article
- Stable high-density and maternally inherited Wolbachia infections in Anopheles moucheti and Anopheles demeilloni mosquitoes.Current biology : CB · 2021Article
- Evidence for natural hybridization and novelRoyal Society open science · 2021Article
- Systematic Review ofPathogens (Basel, Switzerland) · 2021Review
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Authors and funding
9 authors at 3 institutions in 4 countries.
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Abstract
backgroundNatural infections of the endosymbiont bacteria Wolbachia have recently been discovered in populations of the malaria mosquito Anopheles gambiae (s.l.) in Burkina Faso and Mali, West Africa. This Anopheles specific strain wAnga limits the malaria parasite Plasmodium falciparum infections in the mosquito, thus it offers novel opportunities for malaria control.
resultsWe investigated Wolbachia presence in Anopheles arabiensis and Anopheles funestus, which are the two main malaria vectors in the Kilombero Valley, a malaria endemic region in south-eastern Tanzania. We found 3.1% (n = 65) and 7.5% (n = 147) wAnga infection prevalence in An. arabiensis in mosquitoes collected in 2014 and 2016, respectively, while no infection was detected in An. funestus (n = 41). Phylogenetic analysis suggests that at least two distinct strains of wAnga were detected, both belonging to Wolbachia supergroup A and B.
conclusionsTo our knowledge, this is the first confirmation of natural Wolbachia in malaria vectors in Tanzania, which opens novel questions on the ecological and genetic basis of its persistence and pathogen transmission in the vector hosts. Understanding the basis of interactions between Wolbachia, Anopheles mosquitoes and malaria parasites is crucial for investigation of its potential application as a biocontrol strategy to reduce malaria transmission, and assessment of how natural wAnga infections influence pathogen transmission in different ecological settings.
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