Evidence map›Paper›PMID 30545036›Full record

ArticleToxins2018

Acute Toxicity of the Recombinant and Native Phα1β Toxin: New Analgesic from

Eliane Dallegrave, Eliane Taschetto, Mirna Bainy Leal, Flavia Tasmim Techera Antunes, Marcus Vinicius Gomez, Alessandra Hubner de Souza

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Phα1β interaction with the Kv11.1 potassium channel in HEK293 cells transfected with the human ERG channel.The journal of venomous animals and toxins including tropical diseases · 2025
    Article
  3. Article
  4. Analgesic effects of Phα1β toxin: a review of mechanisms of action involving pain pathways.The journal of venomous animals and toxins including tropical diseases · 2021
    Review
  5. Pain-related toxins in scorpion and spider venoms: a face to face with ion channels.The journal of venomous animals and toxins including tropical diseases · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Eliane DallegraveDepartment of Pharmacosciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre, RS 90050-170 Brazil. elianedal@ufcspa.edu.br.ORCID 0000-0001-6586-2080
Eliane TaschettoPostgraduate Program in Genetics and Applied Toxicology, Lutheran University of Brazil, Canoas, RS 92425⁻900, Brazil. etaschetto@gmail.com.
Mirna Bainy LealDepartment of Pharmacology, Institute of Basic Health Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90050-17, Brazil. mirnabl@gmail.com.
Flavia Tasmim Techera AntunesPostgraduate Program in Cellular and Molecular Biology Applied of Health, Lutheran University of Brazil, Canoas, RS 92425⁻900, Brazil. tasmin@hotmail.com.
Marcus Vinicius GomezPostgraduate Program in Health Sciences: Medicine and Biomedicine, Institute of Education and Research, Grupo Santa Casa de Belo Horizonte, Belo Horizonte, MG 30150-240, Brazil. marcusvgomez@gmail.com.ORCID 0000-0002-6082-930X
Alessandra Hubner de SouzaPostgraduate Program in Genetics and Applied Toxicology, Lutheran University of Brazil, Canoas, RS 92425⁻900, Brazil. alessandrahubnersouza@gmail.com.ORCID 0000-0002-6832-2765
Universidade Luterana do Brasil · BRGrupo Santa Casa de Belo Horizonte · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phα1β, a purified peptide from the venom of the spider

Indexed as

AnalgesicsAnimalsFemaleInjections, SpinalKidneyLiverMaleRats, WistarRecombinant ProteinsSpidersSpider VenomsToxicity Tests, AcuteAnalgesicsPhalpha1beta toxin, Phoneutria nigriventerRecombinant ProteinsSpider Venomsacute toxicityPhoneutria nigriventerPhα1β

Identifiers

PMID30545036
PMCPMC6315920
OpenAlexW2904542408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.