Evidence map›Paper›PMID 30544842›Full record

ArticleJournal of clinical medicine2018

Small Airway Disease in Pulmonary Hypertension-Additional Diagnostic Value of Multiple Breath Washout and Impulse Oscillometry.

Frederik Trinkmann, Joshua Gawlitza, Monique Künstler, Julia Schäfer, Michele Schroeter, Julia D Michels, Ksenija Stach, Christina Dösch, Joachim Saur, Martin Borggrefe and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Frederik Trinkmann1st Department of Medicine (Cardiology, Angiology, Pulmonary and Intensive Care), University Medical Center Mannheim, 68135 Mannheim, Germany. frederik.trinkmann@umm.de.ORCID 0000-0001-5877-877X
Joshua GawlitzaInstitute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, 68135 Mannheim, Germany. joshua.gawlitza@umm.de.ORCID 0000-0002-9454-816X
Monique Künstler1st Department of Medicine (Cardiology, Angiology, Pulmonary and Intensive Care), University Medical Center Mannheim, 68135 Mannheim, Germany. monique.kuenstler@t-online.de.
Julia Schäfer1st Department of Medicine (Cardiology, Angiology, Pulmonary and Intensive Care), University Medical Center Mannheim, 68135 Mannheim, Germany. julia.schaefer2@umm.de.
Michele Schroeter1st Department of Medicine (Cardiology, Angiology, Pulmonary and Intensive Care), University Medical Center Mannheim, 68135 Mannheim, Germany. michele.schroeter@gmx.de.
Julia D Michels1st Department of Medicine (Cardiology, Angiology, Pulmonary and Intensive Care), University Medical Center Mannheim, 68135 Mannheim, Germany. julia.michels@umm.de.
Ksenija Stach1st Department of Medicine (Cardiology, Angiology, Pulmonary and Intensive Care), University Medical Center Mannheim, 68135 Mannheim, Germany. ksenija.stach@umm.de.
Christina Dösch1st Department of Medicine (Cardiology, Angiology, Pulmonary and Intensive Care), University Medical Center Mannheim, 68135 Mannheim, Germany. christina.doesch@gmail.com.
Joachim Saur1st Department of Medicine (Cardiology, Angiology, Pulmonary and Intensive Care), University Medical Center Mannheim, 68135 Mannheim, Germany. jsaur@uni-mannheim.de.
Martin Borggrefe1st Department of Medicine (Cardiology, Angiology, Pulmonary and Intensive Care), University Medical Center Mannheim, 68135 Mannheim, Germany. martin.borggrefe@umm.de.
Ibrahim Akin1st Department of Medicine (Cardiology, Angiology, Pulmonary and Intensive Care), University Medical Center Mannheim, 68135 Mannheim, Germany. ibrahim.akin@umm.de.
Heidelberg University · DE

Funding

Markedsmodningsfonden (public grant)MEAMEDMA (internal grant)Ms. Ester Knorr (private donation)
6 · The paper itself

Abstract

Airways obstruction is frequent in patients with pulmonary hypertension (PH). Small airway disease (SAD) was identified as a major contributor to resistance and symptoms. However, it is easily missed using current diagnostic approaches. We aimed to evaluate more elaborate diagnostic tests such as impulse oscillometry (IOS) and SF₆-multiple-breath-washout (MBW) for the assessment of SAD in PH. Twenty-five PH patients undergoing body-plethysmography, IOS and MBW testing were prospectively included and equally matched to pulmonary healthy and non-healthy controls. Lung clearance index (LCI) and acinar ventilation heterogeneity (S

Indexed as

impulse oscillometrylung clearance indexmultiple breath washoutpulmonary hypertensionsmall airway disease

Identifiers

PMID30544842
PMCPMC6306708
OpenAlexW2905021091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.