Evidence map›Paper›PMID 30544796›Full record

ArticleToxins2018

Cyanobacterial Neurotoxin Beta-Methyl-Amino-l-Alanine Affects Dopaminergic Neurons in Optic Ganglia and Brain of

Megan Brooke-Jones, Martina Gáliková, Heinrich Dircksen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Megan Brooke-JonesDepartment of Zoology, Functional Morphology, Stockholm University, Svante Arrhenius väg 18B, S-10691 Stockholm, Sweden. megbrookejones27@gmail.com.
Martina GálikováDepartment of Zoology, Functional Morphology, Stockholm University, Svante Arrhenius väg 18B, S-10691 Stockholm, Sweden. martina.galikova@zoologi.su.se.ORCID 0000-0001-8934-0236
Heinrich DircksenDepartment of Zoology, Functional Morphology, Stockholm University, Svante Arrhenius väg 18B, S-10691 Stockholm, Sweden. dircksen@zoologi.su.se.ORCID 0000-0001-7815-4868
Stockholm University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The non-proteinogenic amino acid beta-methyl-amino-l-alanine (BMAA) is a neurotoxin produced by cyanobacteria. BMAA accumulation in the brain of animals via biomagnification along the food web can contribute to the development of neurodegenerative diseases such as Amyotrophic lateral sclerosis/Parkinsonism dementia complex (ALS/PDC), the latter being associated with a loss of dopaminergic neurons.

Indexed as

Amino Acids, DiaminoAnimalsBacterial ToxinsBrainCyanobacteriaCyanobacteria ToxinsDaphniaDopaminergic NeuronsFemaleGangliaNeurotoxinsReproductionAmino Acids, DiaminoBacterial Toxinsbeta-N-methylamino-L-alanineCyanobacteria ToxinsNeurotoxinsbeta-methyl-amino-l-alanineBMAAcyanobacterial toxinDaphnia magnadopaminergic neuronsneurodegenerationwater flea

Identifiers

PMID30544796
PMCPMC6315693
OpenAlexW2904491870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.