Evidence map›Paper›PMID 30544726›Full record

ReviewNutrients2018

Evidence of Some Natural Products with Antigenotoxic Effects. Part 2: Plants, Vegetables, and Natural Resin.

David López-Romero, Jeannett A Izquierdo-Vega, José Antonio Morales-González, Eduardo Madrigal-Bujaidar, Germán Chamorro-Cevallos, Manuel Sánchez-Gutiérrez, Gabriel Betanzos-Cabrera, Isela Alvarez-Gonzalez, Ángel Morales-González, Eduardo Madrigal-Santillán

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Harnessing the microbiome for cancer therapy.Nature reviews. Microbiology · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Cytogenetic Studies on Genoprotective Effect ofLife (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. Plants (Basel, Switzerland) · 2022
    Review
  16. Complementary and Alternative Therapies in Oncology.International journal of environmental research and public health · 2022
    Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

David López-RomeroInstituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Ex-Hacienda de la Concepción, Tilcuautla, Pachuca de Soto 42080, Hgo, Mexico. david.daloro@gmail.com.
Jeannett A Izquierdo-VegaInstituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Ex-Hacienda de la Concepción, Tilcuautla, Pachuca de Soto 42080, Hgo, Mexico. jizquierdovega@gmail.com.
José Antonio Morales-GonzálezEscuela Superior de Medicina, Instituto Politécnico Nacional, "Unidad Casco de Santo Tomas". Plan de San Luis y Díaz Mirón s/n, Ciudad de México 11340, Mexico. jmorales101@yahoo.com.mx.ORCID 0000-0002-5980-0980
Eduardo Madrigal-BujaidarEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, "Unidad Profesional A. López Mateos". Av. Wilfrido Massieu. Col., Lindavista, Ciudad de México 07738, Mexico. eduardo.madrigal@lycos.com.
Germán Chamorro-CevallosEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, "Unidad Profesional A. López Mateos". Av. Wilfrido Massieu. Col., Lindavista, Ciudad de México 07738, Mexico. gchamcev@yahoo.com.mx.ORCID 0000-0002-8935-9831
Manuel Sánchez-GutiérrezInstituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Ex-Hacienda de la Concepción, Tilcuautla, Pachuca de Soto 42080, Hgo, Mexico. spmtz68@yahoo.com.mx.
Gabriel Betanzos-CabreraInstituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Ex-Hacienda de la Concepción, Tilcuautla, Pachuca de Soto 42080, Hgo, Mexico. gbetanzo@uaeh.edu.mx.ORCID 0000-0003-2027-6904
Isela Alvarez-GonzalezEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, "Unidad Profesional A. López Mateos". Av. Wilfrido Massieu. Col., Lindavista, Ciudad de México 07738, Mexico. isela.alvarez@gmail.com.
Ángel Morales-GonzálezEscuela Superior de Cómputo, Instituto Politécnico Nacional, "Unidad Profesional A. López Mateos". Av. Juan de Dios Bátiz. Col., Lindavista, Ciudad de México 07738, Mexico. anmorales@ipn.mx.ORCID 0000-0003-2920-8078
Eduardo Madrigal-SantillánEscuela Superior de Medicina, Instituto Politécnico Nacional, "Unidad Casco de Santo Tomas". Plan de San Luis y Díaz Mirón s/n, Ciudad de México 11340, Mexico. eomsmx@yahoo.com.mx.ORCID 0000-0003-2264-4598
Instituto Politécnico Nacional · MXUniversidad Autónoma del Estado de Hidalgo · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is one of the leading causes of death worldwide. The agents capable of causing damage to genetic material are known as genotoxins and, according to their mode of action, are classified into mutagens, carcinogens, or teratogens. Genotoxins are also involved in the pathogenesis of several chronic degenerative diseases, including hepatic, neurodegenerative, and cardiovascular disorders; diabetes; arthritis; cancer; chronic inflammation; and ageing. In recent decades, researchers have found novel bioactive phytocompounds able to counteract the effects of physical and chemical mutagens. Several studies have shown the antigenotoxic potential of different fruits and plants (Part 1). In this review (Part 2), we present a research overview conducted on some plants and vegetables (spirulina, broccoli, chamomile, cocoa, ginger, laurel, marigold, roselle, and rosemary), which are frequently consumed by humans. In addition, an analysis of some phytochemicals extracted from those vegetables and the analysis of a resin (propolis),whose antigenotoxic power has been demonstrated in various tests, including the Ames assay, sister chromatid exchange, chromosomal aberrations, micronucleus, and comet assay, was also performed.

Indexed as

Antimutagenic AgentsBiological ProductsPlant PreparationsAnimalsCell LineComet AssayDNA DamageHumansMicePhytochemicalsPropolisSpirulinaVegetablesAntimutagenic AgentsBiological ProductsPhytochemicalsPlant PreparationsPropolisantigenotoxiccancercomet assaymicronucleusplantspropolisvegetables

Identifiers

PMID30544726
PMCPMC6316078
OpenAlexW2904188736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.