ArticleInternational journal of molecular sciences2018
From mRNA Expression of Drug Disposition Genes to In Vivo Assessment of CYP-Mediated Biotransformation during Zebrafish Embryonic and Larval Development.
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Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 42 citations in OpenAlex.
- Mitochondrial protein Mrpl13 regulates zebrafish liver development through the mTORC1-mitochondrial homeostasis pathway.Communications biology · 2026Article
- An Integrated Approach Combining Regulatory Tests inEnvironmental science & technology · 2026Article
- Genotoxicity and gene expression modulation associated with the use of DDVP antiparasitic drugs in aquaculture onFrontiers in veterinary science · 2026Article
- Zebrafish as a translational platform for investigating multi-organ pharmacological interactions of traditional Chinese medicine.Frontiers in pharmacology · 2026Review
- Narrative Review of Patient Cancer Tissue-Derived Zebrafish Xenograft Models for Evaluating Drug Sensitivity as an Avatar Model for Clinical Application.Cancer medicine · 2025Review
- Persistent Metabolic Changes Are Induced by 24 h Low-Dose Lead (Pb) Exposure in Zebrafish Embryos.International journal of molecular sciences · 2025Article
- A review on toxic effects of pesticides in Zebrafish,Toxicology reports · 2024Review
- Intestinal DHA-PA-PG axis promotes digestive organ expansion by mediating usage of maternally deposited yolk lipids.Nature communications · 2024Article
- Diving into drug-screening: zebrafish embryos as an in vivo platform for antimicrobial drug discovery and assessment.FEMS microbiology reviews · 2024Review
- Assessing developmental toxicity and non-CYP mediated biotransformation of two anti-epileptics and their human metabolites in zebrafish embryos and larvae.Current research in toxicology · 2024Article
- Evaluating Phenotypic and Transcriptomic Responses Induced by Low-Level VOCs in Zebrafish: Benzene as an Example.Toxics · 2022Article
- Article
- Developmental Toxicity and Biotransformation of Two Anti-Epileptics in Zebrafish Embryos and Early Larvae.International journal of molecular sciences · 2021Article
- Use of Zebrafish in Drug Discovery Toxicology.Chemical research in toxicology · 2020Review
- Article
- The effect of the antidepressant venlafaxine on gene expression of biotransformation enzymes in zebrafish (Danio rerio) embryos.Environmental science and pollution research international · 2020Article
- ahr2, But Not ahr1a or ahr1b, Is Required for Craniofacial and Fin Development and TCDD-dependent Cardiotoxicity in Zebrafish.Toxicological sciences : an official journal of the Society of Toxicology · 2019Article
- Safety Assessment of Compounds after In Vitro Metabolic Conversion Using Zebrafish Eleuthero Embryos.International journal of molecular sciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 2 countries.
Evy VerbuekenApplied Veterinary Morphology, Department of Veterinary Sciences, University of Antwerp, Wilrijk 2610, Antwerp, Belgium. evy.verbueken@uantwerpen.be.ORCID 0000-0002-7515-2987
Chloé BarsApplied Veterinary Morphology, Department of Veterinary Sciences, University of Antwerp, Wilrijk 2610, Antwerp, Belgium. chloe.bars@uantwerpen.be.
Jonathan S BallBiosciences, College of Life and Environmental Sciences, University of Exeter, Exeter EX4 4QD, UK. J.Ball@exeter.ac.uk.ORCID 0000-0002-3046-3829
Jelena Periz-StanacevZebrafishlab, Veterinary Physiology and Biochemistry, Department of Veterinary Sciences, University of Antwerp, Wilrijk 2610, Antwerp, Belgium. Jelena.perizstanacev@uantwerpen.be.
Waleed F A MareiGamete Research Centre, Veterinary Physiology and Biochemistry, Department of Veterinary Sciences, University of Antwerp, Wilrijk 2610, Antwerp, Belgium. waleed.marei@uantwerpen.be.
Anna TochwinBiosciences, College of Life and Environmental Sciences, University of Exeter, Exeter EX4 4QD, UK. A.Tochwin@exeter.ac.uk.
Isabelle J GabriëlsZebrafishlab, Veterinary Physiology and Biochemistry, Department of Veterinary Sciences, University of Antwerp, Wilrijk 2610, Antwerp, Belgium. Isabelle.gabriels@uantwerpen.be.
Ellen D G MichielsZebrafishlab, Veterinary Physiology and Biochemistry, Department of Veterinary Sciences, University of Antwerp, Wilrijk 2610, Antwerp, Belgium. ellen.michiels@uantwerpen.be.
Evelyn StinckensZebrafishlab, Veterinary Physiology and Biochemistry, Department of Veterinary Sciences, University of Antwerp, Wilrijk 2610, Antwerp, Belgium. evelyn.stinckens@uantwerpen.be.
Lucia VergauwenZebrafishlab, Veterinary Physiology and Biochemistry, Department of Veterinary Sciences, University of Antwerp, Wilrijk 2610, Antwerp, Belgium. lucia.vergauwen@uantwerpen.be.ORCID 0000-0002-6534-7473
Dries KnapenZebrafishlab, Veterinary Physiology and Biochemistry, Department of Veterinary Sciences, University of Antwerp, Wilrijk 2610, Antwerp, Belgium. dries.knapen@uantwerpen.be.ORCID 0000-0003-0472-8114
Chris J Van GinnekenApplied Veterinary Morphology, Department of Veterinary Sciences, University of Antwerp, Wilrijk 2610, Antwerp, Belgium. chris.vanginneken@uantwerpen.be.
Steven J Van CruchtenApplied Veterinary Morphology, Department of Veterinary Sciences, University of Antwerp, Wilrijk 2610, Antwerp, Belgium. steven.vancruchten@uantwerpen.be.ORCID 0000-0002-3144-1840
University of Antwerp · BEUniversity of Exeter · GB
Funding
No grant is acknowledged in the PubMed record.
Abstract
The zebrafish (
Indexed as
Gene Expression Regulation, DevelopmentalAnimalsATP Binding Cassette Transporter, Subfamily B, Member 1BiotransformationCytochrome P-450 Enzyme SystemEmbryonic DevelopmentEmbryo, NonmammalianLarvaOxazinesPharmaceutical PreparationsRNA, MessengerZebrafishATP Binding Cassette Transporter, Subfamily B, Member 1Cytochrome P-450 Enzyme SystemOxazinesPharmaceutical PreparationsresorufinRNA, Messengeractivityand expressionbiotransformationcytochrome P450developmentdrug transporterembryolarvaphase IIzebrafish
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.