Evidence map›Paper›PMID 30544589›Full record

ArticleMolecules (Basel, Switzerland)2018

Supercritical CO₂ Extraction of

Stefania Sut, Irene Boschiero, Miriam Solana, Mario Malagoli, Alberto Bertucco, Stefano Dall'Acqua

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Glucosinolate Derivatives: Emerging Anti-Inflammatory Agents.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  4. Plants (Basel, Switzerland) · 2025
    Review
  5. KyohMolecules (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Stefania SutDAFNAE, Department of Agronomy, Food, Natural Resources, Animals and Environment, Agripolis Campus, University of Padova, 35020 Legnaro (PD), Italy. stefania.sut@studenti.unipd.it.
Irene BoschieroDepartment of Pharmaceutical and Pharmacological Sciences, University of Padua, Via Marzolo 5, 35131 Padua, Italy. boschieroirene@gmail.com.
Miriam SolanaDepartment of Industrial Engineering DII, University of Padova, Via Marzolo 9, 35131 Padua, Italy. mirivillas@gmail.com.
Mario MalagoliDAFNAE, Department of Agronomy, Food, Natural Resources, Animals and Environment, Agripolis Campus, University of Padova, 35020 Legnaro (PD), Italy. mario.malagoli@unipd.it.
Alberto BertuccoDepartment of Industrial Engineering DII, University of Padova, Via Marzolo 9, 35131 Padua, Italy. alberto.bertucco@unipd.it.
Stefano Dall'AcquaDepartment of Pharmaceutical and Pharmacological Sciences, University of Padua, Via Marzolo 5, 35131 Padua, Italy. stefano.dallacqua@unipd.it.ORCID 0000-0001-8264-6953
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

resultsWater resulted the ideal co-solvent, allowing the extraction of glucosinolates in comparable amounts to the classical procedure with boiling water, as it can be carried out at mild temperatures (45 °C vs. >100 °C). Increasing the pressure improved the GLS extraction. On the other hand polyphenol extraction under the studied conditions was not influenced by pressure and temperature variations. The in vitro antioxidant effect of the obtained extracts was also measured, showing significant activity in the DPPH and FC tests.

conclusionsThe GLS, flavonoids and lipids composition of the obtained extracts was studied, showing the presence of numerous antioxidant constituents useful for nutraceutical applications. The extraction method using SCO₂ and water as co-solvent presents advantages in terms of safety because these solvents are generally recognised as safe. Water as cosolvent at 8% resulted useful for the extraction of both glucosinolates and phenolics in good amount and is environmentally acceptable as well as safe for food production.

Indexed as

AntioxidantsBiphenyl CompoundsBrassicaceaeCarbon DioxideChromatography, LiquidGlucosinolatesLipidsPhenolsPhytochemicalsPicratesPlant ExtractsPlant LeavesPressureSecondary MetabolismSolventsSpectrometry, Mass, Electrospray Ionization1,1-diphenyl-2-picrylhydrazylAntioxidantsBiphenyl CompoundsCarbon DioxideGlucosinolatesLipidsPhenolsPhytochemicalsPicratesPlant ExtractsSolventsantioxidant activityEruca sativaglucosinolatesupercritical CO2

Identifiers

PMID30544589
PMCPMC6321549
OpenAlexW2904870291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.