Evidence map›Paper›PMID 30544543›Full record

ArticleNutrients2018

Botanical Formulation HX109 Ameliorates TP-Induced Benign Prostate Hyperplasia in Rat Model and Inhibits Androgen Receptor Signaling by Upregulating Ca

Seonung Lim, Wonwoo Lee, Doo Suk Lee, In-Jeong Nam, Nayoung Yun, Yoonseon Jeong, Taewoong Rho, Sunyoung Kim

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Effects of larval extracts from identifiedFood science & nutrition · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Seonung LimSchool of Biological Sciences, Seoul National University, Seoul 151-742, Korea. kindman10@snu.ac.kr.
Wonwoo LeeViroMed Co. Ltd., Building 203, Seoul National University, Seoul 151-742, Korea. wwlee@viromed.co.kr.
Doo Suk LeeViroMed Co. Ltd., Building 203, Seoul National University, Seoul 151-742, Korea. dslee@viromed.co.kr.
In-Jeong NamViroMed Co. Ltd., Building 203, Seoul National University, Seoul 151-742, Korea. ijnam@viromed.co.kr.
Nayoung YunViroMed Co. Ltd., Building 203, Seoul National University, Seoul 151-742, Korea. nyyun@viromed.co.kr.
Yoonseon JeongViroMed Co. Ltd., Building 203, Seoul National University, Seoul 151-742, Korea. ysjeong@viromed.co.kr.
Taewoong RhoCollege of Pharmacy and Integrated Research Institute of Pharmaceutical Sciences, The Catholic University of Korea, Bucheon 14662, Korea. karlwho@naver.com.
Sunyoung KimViroMed Co. Ltd., Building 203, Seoul National University, Seoul 151-742, Korea. sk@viromed.co.kr.ORCID 0000-0002-1736-9088
Seoul National University · KRCatholic University of Korea · KR

Funding

National Research Foundation of Korea 2014R1A1A2055890
6 · The paper itself

Abstract

Benign prostatic hyperplasia (BPH) is a common disease in the elderly male population throughout the world. Among other factors, androgen dysregulation has been known to play major roles in its pathogenesis. HX109 is a botanical formulation prepared from a mixture of

Indexed as

Prostatic HyperplasiaActivating Transcription Factor 3AnimalsCalciumCalcium-Calmodulin-Dependent Protein Kinase KinaseCell Line, TumorHumansMalePlant PreparationsProstateProtective AgentsRatsRats, Sprague-DawleyReceptors, AndrogenSignal TransductionTestosterone PropionateActivating Transcription Factor 3CalciumCalcium-Calmodulin-Dependent Protein Kinase KinaseCAMKK2 protein, humanPlant PreparationsProtective AgentsReceptors, AndrogenTestosterone PropionateAR signalingATF3BPHCaMKKβHX109

Identifiers

PMID30544543
PMCPMC6316726
OpenAlexW2905342200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.