Evidence map›Paper›PMID 30544526›Full record

ArticleJournal of clinical medicine2018

Anti-Mycobacterial Antibodies in Paired Cerebrospinal Fluid and Serum Samples from Japanese Patients with Multiple Sclerosis or Neuromyelitis Optica Spectrum Disorder.

Kazumasa Yokoyama, Davide Cossu, Yasunobu Hoshino, Yuji Tomizawa, Eiichi Momotani, Nobutaka Hattori

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Autoimmune Diseases and Mycobacterial Infection.Diseases (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
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  5. Article
  6. Review
  7. Life (Basel, Switzerland) · 2023
    Article
  8. Lateral-flow assays for bovine paratuberculosis diagnosis.Frontiers in veterinary science · 2023
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Proposing BCG Vaccination forMicroorganisms · 2020
    Review
  18. Article
  19. PtpA and PknG Proteins Secreted byJournal of inflammation research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kazumasa YokoyamaDepartment of Neurology, Juntendo University School of Medicine, Tokyo 113-8421, Japan. kazumasa@juntendo.ac.jp.
Davide CossuDepartment of Neurology, Juntendo University School of Medicine, Tokyo 113-8421, Japan. davide@juntendo.ac.jp.ORCID 0000-0002-0557-9467
Yasunobu HoshinoDepartment of Neurology, Juntendo University School of Medicine, Tokyo 113-8421, Japan. yshoshi@juntendo.ac.jp.
Yuji TomizawaDepartment of Neurology, Juntendo University School of Medicine, Tokyo 113-8421, Japan. tmzw1977@gmail.com.
Eiichi MomotaniDepartment of Human-care, Tohto College of Health Sciences, Saitama 366-0052, Japan. eiichimomotani@gmail.com.ORCID 0000-0003-4765-1866
Nobutaka HattoriDepartment of Neurology, Juntendo University School of Medicine, Tokyo 113-8421, Japan. nhattori@juntendo.ac.jp.
Juntendo University · JPTohto College of Health Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Local synthesis of antibodies and presence of oligoclonal bands in the cerebrospinal fluid (CSF) are hallmarks of multiple sclerosis (MS). We investigated the frequency of antibodies against mycobacterial and relevant human epitopes in the CSF of patients with MS or neuromyelitis optica spectrum disorder (NMOSD) and whether these antibodies differed from those present in the serum. Matched serum and CSF samples from 46 patients with MS, 42 patients with NMOSD, and 29 age-matched and sex-matched control subjects were screened retrospectively for the presence of antibodies against

Indexed as

cerebrospinal fluidhumoral responseJapanMBPmultiple sclerosisMycobacteriumNMOSD

Identifiers

PMID30544526
PMCPMC6306948
OpenAlexW2903615433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.