Evidence map›Paper›PMID 30544510›Full record

ArticleInternational journal of molecular sciences2018

Matrix Metalloproteinase Response of Dendritic Cell, Gingival Epithelial Keratinocyte, and T-Cell Transwell Co-Cultures Treated with

Amber M Bates, Carol L Fischer, Vrushali P Abhyankar, Georgia K Johnson, Janet M Guthmiller, Ann Progulske-Fox, Kim A Brogden

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Three dimensional (3D) gingival models in periodontal research: a systematic review.Journal of materials science. Materials in medicine · 2023
    Pooled it
  2. Pooled it
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  12. Matrix Metalloproteinases: How Much Can They Do?International journal of molecular sciences · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Amber M BatesIowa Institute for Oral Health Research, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA. ambates@wisc.edu.ORCID 0000-0002-5184-4532
Carol L FischerDepartment of Biology, Waldorf University, Forest City, IA 50436, USA. carol.fischer@waldorf.edu.
Vrushali P AbhyankarDepartment of Periodontology, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38103, USA. vabhyank@uthsc.edu.
Georgia K JohnsonDepartment of Periodontics, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA. georgia-johnson@uiowa.edu.
Janet M GuthmillerCollege of Dentistry, University of Nebraska Medical Center, Lincoln, NE 68583, USA. janet.guthmiller@unmc.edu.
Ann Progulske-FoxCenter for Molecular Microbiology and Department of Oral Biology, University of Florida, Gainesville, FL 32603, USA. APFOX@dental.ufl.edu.ORCID 0000-0001-5911-5935
Kim A BrogdenIowa Institute for Oral Health Research, College of Dentistry, The University of Iowa, Iowa City, IA 52242, USA. kim-brogden@uiowa.edu.ORCID 0000-0003-3296-3867
University of Iowa · USUniversity of Florida · USUniversity of Nebraska Medical Center · USUniversity of Tennessee Health Science Center · USWaldorf College · US

Funding

University of Iowa Institutional Training Program in Oral Health ResearchT90DE023520 · NIDCR · UNIVERSITY OF IOWA · PI STEVEN M. LEVY · 2013 to 2026
$5.6M
Defensin-induced Adaptive Immunity to HagBR01DE014390 · NIDCR · UNIVERSITY OF IOWA · PI BROGDEN, KIM A · 2003 to 2014
$3.4M
National Institute of Dental and Craniofacial Research R01 DE014390National Institute of Dental and Craniofacial Research T90 DE023520NIDCR NIH HHS T90 DE023520
6 · The paper itself

Abstract

Matrix metalloproteinases (MMPs) are enzymes involved in periodontal tissue destruction. Hemagglutinin B (HagB) from the periodontal pathogen

Indexed as

CD4-Positive T-LymphocytesCell Culture TechniquesCoculture TechniquesDendritic CellsGingivaHemagglutininsHumansKeratinocytesMatrix Metalloproteinase 1Matrix MetalloproteinasesPorphyromonas gingivalisT-LymphocytesHemagglutininsMatrix Metalloproteinase 1Matrix MetalloproteinasesMMP1 protein, humanhemagglutinin-Bmatrix metalloproteinasestranswell co-cultures

Identifiers

PMID30544510
PMCPMC6321455
OpenAlexW2905294538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.