Evidence map›Paper›PMID 30544378›Full record

ArticleMedicine2018

Transition of a Mallory-Weiss syndrome to a Boerhaave syndrome confirmed by anamnestic, necroscopic, and autopsy data: A case report.

Maria Cuccì, Fiorella Caputo, Giulio Fraternali Orcioni, Anna Roncallo, Francesco Ventura

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Boerhaave Syndrome-Narrative Review.Diagnostics (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Article
  7. A Case of Candida Empyema in a Patient With Esophagopleural Fistula.Journal of community hospital internal medicine perspectives · 2023
    Article
  8. Review
  9. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  10. Boerhaave syndrome.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  11. Article
  12. Boerhaave syndrome due to excessive alcohol consumption: two case reports.International journal of emergency medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maria CuccìDepartment of Legal and Forensic Medicine, University of Genova, Genova.
Fiorella CaputoDepartment of Legal and Forensic Medicine, University of Genova, Genova.
Giulio Fraternali OrcioniDepartment of Clinical Pathology, S. Croce e Carle Hospital, Cuneo, Italy.
Anna RoncalloDepartment of Legal and Forensic Medicine, University of Genova, Genova.
Francesco VenturaDepartment of Legal and Forensic Medicine, University of Genova, Genova.
University of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleSpontaneous esophageal rupture (Boerhaave syndrome) is a rare, though frequently fatal, event. It is generally caused by a sudden increase in pressure inside the esophagus. In some cases, full-thickness perforations of the esophagus may develop from previous lesions that initially involve only the esophageal mucosa (Mallory-Weiss syndrome) and which, following further triggering events, give rise to a transmural lesion. PATIENT CONCERNS: Here, we present the case of a 45-year-old subject who suddenly died of acute cardio-respiratory failure, an autopsy was performed to identify the cause of death. DIAGNOSIS, INTERVENTIONS, AND OUTCOMES: The autopsy examination revealed a full-thickness rupture of the esophageal wall. Through the integration of necroscopy findings, anamnestic data, and histopathological examination, it has been possible to establish that complete esophageal rupture resulted from the evolution of a previous partial lesion of the esophageal wall, and that an untreated Mallory-Weiss syndrome evolved into a rapidly fatal Boerhaave syndrome. LESSONS: This case shows that distal esophageal tears, rather than constituting a distinct entity, may be part of a spectrum of diseases and that a partial lesion of the esophageal wall caused by barogenic injury may evolve into a full-thickness rupture following further barotraumas.

Indexed as

Death, SuddenDisease ProgressionEsophageal DiseasesEsophageal PerforationFatal OutcomeHumansMaleMallory-Weiss SyndromeMediastinal DiseasesMiddle AgedRupture, SpontaneousSpontaneous Perforation

Identifiers

PMID30544378
PMCPMC6310542
OpenAlexW2904817608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.