Evidence map›Paper›PMID 30544190›Full record

ArticleInternational journal of epidemiology2019

Precision nutrition: hype or hope for public health interventions to reduce obesity?

Angeline Chatelan, Murielle Bochud, Katherine L Frohlich

Open access · bronzeAbstract read
In one paragraph

Article in International journal of epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Cost-Effectiveness of Personalised Nutrition in Adults With Overweight and Obesity: PREVENTOMICS Studies in Poland and the UK.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Personalising dietary advice for disease prevention: concepts and experiences.Pflugers Archiv : European journal of physiology · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Machine Learning in Nutrition Research.Advances in nutrition (Bethesda, Md.) · 2022
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Scientific challenges for precision public health.Journal of epidemiology and community health · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Angeline ChatelanInstitute of Social and Preventive Medicine, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Murielle BochudInstitute of Social and Preventive Medicine, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Katherine L FrohlichDépartement de médecine sociale et préventive, Ecole de Santé Publique & Institut de recherche en santé publique de l'Université de Montréal, Université de Montréal, Montreal, QC, Canada.
Institute of Social and Preventive Medicine · CHUniversité de Montréal · CAUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-income countries are experiencing an obesity epidemic that follows a socioeconomic gradient, affecting groups of lower socioeconomic status disproportionately. Recent clinical findings have suggested new perspectives for the prevention and treatment of obesity, using personalized dietary approaches. Precision nutrition (PN), also called personalized nutrition, has been developed to deliver more preventive and practical dietary advice than 'one-size-fits-all' guidelines. With interventions becoming increasingly plausible at a large scale thanks to artificial intelligence and smartphone applications, some have begun to view PN as a novel way to deliver the right dietary intervention to the right population. We argue that large-scale PN, if taken alone, might be of limited interest from a public health perspective. Building on Geoffrey Rose's theory regarding the differences in individual and population causes of disease, we show that large-scale PN can only address some individual causes of obesity (causes of cases). This individual-centred approach is likely to have a small impact on the distribution of obesity at a population level because it ignores the population causes of obesity (causes of incidence). The latter are embedded in the populations' social, cultural, economic and political contexts that make environments obesogenic. Additionally, the most socially privileged groups in the population are the most likely to respond to large-scale PN interventions. This could have the undesirable effect of widening social inequalities in obesity. We caution public health actors that interventions based only on large-scale PN are unlikely, despite current expectations, to improve dietary intake or reduce obesity at a population level.

Indexed as

DietPrecision MedicinePublic Health PracticeHealth PromotionHumansObesitySocioeconomic Factorsobesityobesogenic environmentspersonalized nutritionpopulation interventionsPrecision nutritionsocial inequalities in health

Identifiers

PMID30544190
PMCPMC6469305
OpenAlexW2904109511

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.