Evidence map›Paper›PMID 30543564›Full record

ArticleThe Pediatric infectious disease journal2019

Predictors of Poor Outcomes Among Infants With Respiratory Syncytial Virus-associated Acute Lower Respiratory Infection in Botswana.

Sweta M Patel, Lisa Spees, Marek Smieja, Kathy Luinstra, Andrew P Steenhoff, Kristen A Feemster, Tonya Arscott-Mills, Sefelani Boiditswe, Mohamed Z Patel, Samir S Shah and 2 more

Abstract read
In one paragraph

Article in The Pediatric infectious disease journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sweta M PatelFrom the Division of Pulmonary, Allergy, and Critical Care Medicine, Duke University, Durham, North Carolina.
Lisa SpeesThe Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Marek SmiejaDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Kathy LuinstraDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Andrew P SteenhoffGlobal Health Center.
Kristen A FeemsterGlobal Health Center.
Tonya Arscott-MillsGlobal Health Center.
Sefelani BoiditsweBotswana-UPenn Partnership, Gaborone, Botswana.
Mohamed Z PatelUniversity of Botswana School of Medicine, Gaborone, Botswana.
Samir S ShahDivision of Hospital Medicine.
Coleen K CunninghamDivision of Pediatric Infectious Diseases, Duke University, Durham, North Carolina.
Matthew S KellyDivision of Pediatric Infectious Diseases, Duke University, Durham, North Carolina.

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ROBERT GROSS · 1999 to 2026
$78.6M
Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5M
UNC-CH TRAINING PROGRAM IN HEALTH SERVICES RESEARCHT32HS000032 · AHRQ · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HOLMES, GEORGE M · 1989 to 2024
$8.2M
INTERDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASET32HL007538 · NHLBI · DUKE UNIVERSITY · PI LEE, PATTY J, PALMER, SCOTT M · 1985 to 2019
$7.2M
Duke Research Training Program for PediatriciansT32HD043029 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2002 to 2017
$3.7M
Institutional Training Grant in Pediatric Infectious DiseaseT32HD060558 · NICHD · DUKE UNIVERSITY · PI CUNNINGHAM, COLEEN K. · 2011 to 2015
$1.0M
Nasopharyngeal Microbiome and Risk of Bacterial Pathogen Colonization in InfantsK23AI135090 · NIAID · DUKE UNIVERSITY · PI KELLY, MATTHEW SCOTT · 2018 to 2022
$860k
AHRQ HHS T32 HS000032NHLBI NIH HHS T32 HL007538NIAID NIH HHS K23 AI135090NIAID NIH HHS P30 AI045008NIAID NIH HHS P30 AI064518NICHD NIH HHS L40 HD073040NICHD NIH HHS T32 HD043029NICHD NIH HHS T32 HD060558
6 · The paper itself

Abstract

Among children 1-23 months of age with respiratory syncytial virus-associated acute lower respiratory infection in Botswana, young age (<6 months), household use of wood as a cooking fuel, moderate or severe malnutrition and oxygen saturation <90% on room air were independent predictors of clinical nonresponse at 48 hours. Among HIV-uninfected infants less than six months of age, HIV exposure was associated with a higher risk of in-hospital mortality.

Indexed as

BotswanaFemaleHumansInfantMalePneumonia, ViralPrognosisRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsTreatment Outcome

Identifiers

PMID30543564
PMCPMC6465100

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.