Evidence map›Paper›PMID 30543556›Full record

ReviewCurrent opinion in anaesthesiology2019

Pulse pressure and perioperative stroke.

Abbas Al-Qamari, Ibukunoluwa Adeleke, Adam Kretzer, Charles W Hogue

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in anaesthesiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. In Vivo Quantification of Cardiac-Pulsatility-Induced Motion Before and After Double-Branched Endovascular Aortic Arch Repair.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2023
    Article
  5. A computational study of aortic reconstruction in single ventricle patients.Biomechanics and modeling in mechanobiology · 2023
    Article
  6. Review
  7. Article
  8. Wide pulse pressure: A clinical review.Journal of clinical hypertension (Greenwich, Conn.) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Abbas Al-QamariDepartment of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Ibukunoluwa Adeleke
Adam Kretzer
Charles W Hogue
Northwestern University · US

Funding

Continuous Cerebral Autoregulation Monitoring to Reduce Brain Injury from CardiacR01HL092259 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HOGUE, CHARLES W · 2009 to 2018
$3.4M
NHLBI NIH HHS R01 HL092259
6 · The paper itself

Abstract

purpose of reviewCentral pulse pressure (PP), a marker of vascular stiffness, is a novel indicator of risk for perioperative morbidity including ischemic stroke. Appreciation for the mechanism by which vascular stiffness leads to organ dysfunction along with understanding its clinical detection may lead to improved patient management. RECENT

findingsVascular stiffness is associated with increased mortality and neurologic, cardiac, and renal injury in nonsurgical and surgical patients. Left ventricular hypertrophy and diastolic dysfunction along with microcirculatory changes in the low vascular resistance, high blood flow, cerebral and renal vasculature are seen in patients with vascular stiffness. Pulse wave velocity and the augmentation index have higher sensitivity for detecting of vascular stiffness than peripheral PP as the hemodynamic consequences of vascular stiffness are secondary to alterations in the central vasculature. Vascular stiffness alters cerebral autoregulation, resulting in a high likelihood of having a lower limit of autoregulation more than 65 mmHg during surgery. Vascular stiffness may predispose to cerebral hypoperfusion, increasing vulnerability to ischemic stroke, postoperative delirium, and acute kidney injury. SUMMARY: Vascular stiffness leads to alterations in cerebral, cardiac, and renal hemodynamics increasing the risk of perioperative ischemic stroke and neurologic, cardiac, and renal dysfunction.

Indexed as

Perioperative PeriodAcute Kidney InjuryBlood PressureCardiac Surgical ProceduresEmergence DeliriumHumansMonitoring, PhysiologicPulse Wave AnalysisStrokeVascular Stiffness

Identifiers

PMID30543556
PMCPMC6310080
OpenAlexW2905152972

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.