Evidence map›Paper›PMID 30543325›Full record

ArticleeLife2018

Gene flow mediates the role of sex chromosome meiotic drive during complex speciation.

Colin D Meiklejohn, Emily L Landeen, Kathleen E Gordon, Thomas Rzatkiewicz, Sarah B Kingan, Anthony J Geneva, Jeffrey P Vedanayagam, Christina A Muirhead, Daniel Garrigan, David L Stern and 1 more

Abstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Genetics and genomics of hybridization.Nature reviews. Genetics · 2026
    Review
  2. Article
  3. Genomic analyses inEvolution letters · 2026
    Article
  4. Article
  5. The evolutionary genomics of meiotic drive.Molecular biology and evolution · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Meiotic drive against chromosome fusions in butterfly hybrids.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2024
    Article
  13. Review
  14. Article
  15. New perspectives on the causes and consequences of male meiotic drive.Current opinion in genetics & development · 2023
    Review
  16. Review
  17. Review
  18. Proliferation and dissemination of killer meiotic drive loci.Current opinion in genetics & development · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Colin D MeiklejohnSchool of Biological Sciences, University of Nebraska, Lincoln, United States.ORCID 0000-0003-2708-8316
Emily L LandeenDepartment of Biology, University of Rochester, New York, United States.
Kathleen E GordonSchool of Biological Sciences, University of Nebraska, Lincoln, United States.
Thomas RzatkiewiczDepartment of Biology, University of Rochester, New York, United States.
Sarah B KinganDepartment of Biology, University of Rochester, New York, United States.
Anthony J GenevaDepartment of Biology, University of Rochester, New York, United States.
Jeffrey P VedanayagamDepartment of Biology, University of Rochester, New York, United States.
Christina A MuirheadDepartment of Biology, University of Rochester, New York, United States.
Daniel GarriganDepartment of Biology, University of Rochester, New York, United States.ORCID 0000-0002-7000-6788
David L SternJanelia Research Campus, Howard Hughes Medical Institute, Virginia, United States.ORCID 0000-0002-1847-6483
Daven C PresgravesDepartment of Biology, University of Rochester, New York, United States.

Funding

Genomics of complex speciation between Drosophila simulans and D. mauritianaR01OD010548 · OD · UNIVERSITY OF ROCHESTER · PI GARRIGAN, DANIEL WILLIAM, PRESGRAVES, DAVEN C · 2012 to 2015
$1.5M
Investigating the special role of sex chromosomes in speciation: discovering the molecular identities, functions, and evolutionary histories of X-linked hybrid male sterility genes in DrosophilaR01GM123194 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI MEIKLEJOHN, COLIN D · 2017 to 2020
$1.3M
NIGMS NIH HHS 1R01GM123194-01A1NIGMS NIH HHS 1R01OD010548-01A1NIGMS NIH HHS R01 GM123194NIH HHS R01 OD010548
6 · The paper itself

Abstract

During speciation, sex chromosomes often accumulate interspecific genetic incompatibilities faster than the rest of the genome. The drive theory posits that sex chromosomes are susceptible to recurrent bouts of meiotic drive and suppression, causing the evolutionary build-up of divergent cryptic sex-linked drive systems and, incidentally, genetic incompatibilities. To assess the role of drive during speciation, we combine high-resolution genetic mapping of X-linked hybrid male sterility with population genomics analyses of divergence and recent gene flow between the fruitfly species,

Indexed as

Biological EvolutionGenetic SpeciationAnimalsDrosophilaDrosophila simulansGene FlowInfertility, MaleMaleMeiosisSpecies SpecificityX ChromosomeY ChromosomeDrosophila mauritianaDrosophila simulansevolutionary biologygeneticsgenomicsspeciation

Identifiers

PMID30543325
PMCPMC6292695

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.