Evidence map›Paper›PMID 30543038›Full record

ArticleTechniques in coloproctology2018

Risk of postoperative morbidity in patients having bowel resection for colonic Crohn's disease.

Igors Iesalnieks, A Spinelli, M Frasson, F Di Candido, B Scheef, N Horesh, M Iborra, H J Schlitt, A El-Hussuna

Abstract readEvaluation StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Techniques in coloproctology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Igors IesalnieksDepartment of Surgery, University Clinic of Regensburg, Regensburg, Germany. iesalnieks_igors@hotmail.com.
A SpinelliDivision of Colon and Rectal Surgery, Humanitas Clinical and Research Center, Milan, Rozzano, Italy.
M FrassonDepartment of General Surgery, Colorectal Unit, La Fe University and Polytechnic Hospital, Valencia, Spain.
F Di CandidoDivision of Colon and Rectal Surgery, Humanitas Clinical and Research Center, Milan, Rozzano, Italy.
B ScheefDepartment of Surgery, Ålborg University Hospital, Ålborg, Denmark.
N HoreshDepartment of Surgery and Transplantation, Chaim Sheba Medical Center (affiliated with the Faculty of Medicine, Tel Aviv University), Ramat Gan, Israel.
M IborraDepartment of Gastroenterology, IBD Unit, La Fe University and Polytechnic Hospital, Valencia, Spain.
H J SchlittDepartment of Surgery, University Clinic of Regensburg, Regensburg, Germany.
A El-HussunaDepartment of Surgery, Ålborg University Hospital, Ålborg, Denmark.
Hospital Universitari i Politècnic La Fe · ESHumanitas University · ITTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the present multicenter study was to analyze the incidence and risk factors associated with postoperative morbidity in patients who had colorectal resection for colonic Crohn's disease.

methodsConsecutive patients undergoing colorectal resection for colonic Crohn's disease at seven surgical units in 1992-2017 were included. Exclusion criteria were: proctectomy for perianal disease, surgery for cancer, previous colectomies, surgery before 1998. Abdominal colectomy and proctocolectomy were defined as extended resections; all other operations were classified as segmental resections. Postoperative intraabdominal septic complications (IASC) were: anastomotic leaks, peritonitis and abscess.

resultsOne hundred ninety-nine patients met the inclusion criteria: 116 patients had segmental resections and extended resections were performed in 83 patients. An anastomosis was constructed in 122 patients and an additional stoma was formed in 15 of those cases. Segmental resections were performed significantly more frequently in stricturing or penetrating disease (93% vs. 61%, p < 0.001) and were completed by an anastomosis more often than extended resections (78% vs. 37%, p < 0.001). The overall IASC rate was 17%. On multivariate analysis, formation of an anastomosis (Hazard ratio 2.9; 95% CI 1.1-7.7; p = 0.036) and preoperative hemoglobin level of < 10 g/dl (Hazard ratio 3.1; 95% CI 1.1-9.1; p = 0.034) were associated with an increase of postoperative IASC rate. Preoperative medication did not influence postoperative outcome.

conclusionsSevere preoperative anemia is associated with an increased postoperative morbidity. Resections completed by an anastomosis pose an increased postoperative complication risk in patients with colonic Crohn's disease as compared to resections without an anastomosis.

Indexed as

AdolescentAdultAnastomosis, SurgicalAnemiaColectomyColonCrohn DiseaseFemaleHumansIncidenceMaleMultivariate AnalysisPostoperative ComplicationsPreoperative PeriodRetrospective StudiesRisk FactorsColonic disease, postoperative morbidityCrohn’s diseaseSurgery

Identifiers

PMID30543038
OpenAlexW2904834425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.