ReviewF1000Research2018
Ovarian ageing and the impact on female fertility.
Review in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Potency of Adipose-Derived Mesenchymal Stem Cells to Increase Ovarian Function in Primary Ovarian Insufficiency: A Systematic Review of in vivo Studies.Gynecologic and obstetric investigation · 2025Pooled it
- Conserved signaling pathways and transcriptional regulators drive ovarian aging across species.Poultry science · 2026Article
- Insulin-like growth factor 1 as a key paracrine mediator in mesenchymal stem cell-based intervention for ovarian ageing: a review.Journal of ovarian research · 2026Review
- Stage-specific machine learning prediction of cumulative live birth in women with diminished ovarian reserve.Frontiers in endocrinology · 2026Article
- Oxidative Stress-Telomere Axis in IVF: Molecular Mechanisms, Biomarkers, and Clinical Translation.International journal of molecular sciences · 2025Review
- Pterostilbene enhances reproductive outcomes and oocyte quality in aged mice without adverse effects.Aging · 2025Article
- Role of AMP-Activated Protein Kinase (AMPK) in Female Reproduction: A Review.International journal of molecular sciences · 2025Review
- Fertility Preservation and Treatment Coverage Among United States Plastic Surgery Trainees.Plastic and reconstructive surgery. Global open · 2025Article
- Nano-encapsulated senolytic cocktail attenuates germ cell senescence in female mice.Cellular and molecular life sciences : CMLS · 2025Article
- High-altitude hypoxia exposure alters follicular metabolome and oocyte developmental potential in women.Archives of gynecology and obstetrics · 2025Article
- Developmental programming: preconceptional and gestational exposure of sheep to biosolids on offspring ovarian dynamics†.Biology of reproduction · 2025Article
- Evaluation of pregnancy outcomes in patients with a history of bariatric surgery.Frontiers in medicine · 2025Article
- Reproductive History and Infertility Risk: Insights from the 2017-2020 National Health and Nutrition Examination Survey.International journal of women's health · 2025Article
- The Right to Freeze Oocyte for Women in Iranian Fertility Centers: A Qualitative Study.Medical journal of the Islamic Republic of Iran · 2025Article
- Cross-species regulatory network analysis identifies FOXO1 as a driver of ovarian follicular recruitment.Scientific reports · 2024Article
- TET1 overexpression affects cell proliferation and apoptosis in aging ovaries.Journal of assisted reproduction and genetics · 2024Article
- The Application of Nano Drug Delivery Systems in Female Upper Genital Tract Disorders.Pharmaceutics · 2024Review
- Review
- Identification of metabolomic changes and potential therapeutic targets during ovarian aging.Aging · 2024Article
- Anti-Müllerian hormone does not predict cumulative pregnancy rate in non-infertile women following four IUI cycles with donor sperm.Journal of assisted reproduction and genetics · 2024Observational
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Female fertility decreases with increasing age, a reflection of declining oocyte quantity and quality. The menopausal transition occurs when the oocyte quantity falls below a threshold level. The pattern of follicular depletion as well as the factors, timing and mechanisms surrounding both declining oocyte number and oocyte quality remain incompletely understood. Further studies are needed to examine the factors involved and develop predictive models and biomarkers to assist in the management of age-related subfertility. This review summarises the current knowledge addressing the ageing ovary and its impact on fertility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.