Evidence map›Paper›PMID 30542554›Full record

ArticleChemical science2018

Fluorescent probes guided by a new practical performance regulation strategy to monitor glutathione in living systems.

Mengyao She, Zhaohui Wang, Tianyou Luo, Bing Yin, Ping Liu, Jing Liu, Fulin Chen, Shengyong Zhang, Jianli Li

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 48 citations in OpenAlex.

  1. A modular template for the design of thiol-triggered sensors and prodrugs.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2021
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Mengyao SheMinistry of Education Key Laboratory of Synthetic and Natural Functional Molecule Chemistry , College of Chemistry & Materials Science , Northwest University , Xi'an , Shaanxi 710127 , PR China . Email: lijianli@nwu.edu.cn.ORCID 0000-0002-5483-7493
Zhaohui WangMinistry of Education Key Laboratory of Synthetic and Natural Functional Molecule Chemistry , College of Chemistry & Materials Science , Northwest University , Xi'an , Shaanxi 710127 , PR China . Email: lijianli@nwu.edu.cn.ORCID 0000-0003-3891-9621
Tianyou LuoMinistry of Education Key Laboratory of Synthetic and Natural Functional Molecule Chemistry , College of Chemistry & Materials Science , Northwest University , Xi'an , Shaanxi 710127 , PR China . Email: lijianli@nwu.edu.cn.
Bing YinMinistry of Education Key Laboratory of Synthetic and Natural Functional Molecule Chemistry , College of Chemistry & Materials Science , Northwest University , Xi'an , Shaanxi 710127 , PR China . Email: lijianli@nwu.edu.cn.ORCID 0000-0001-8668-9504
Ping LiuMinistry of Education Key Laboratory of Synthetic and Natural Functional Molecule Chemistry , College of Chemistry & Materials Science , Northwest University , Xi'an , Shaanxi 710127 , PR China . Email: lijianli@nwu.edu.cn.
Jing LiuKey Laboratory of Resource Biology and Modern Biotechnology in Western China , Ministry of Education , Northwest University , 229 TaiBai North Road , Xi'an , Shaanxi Province 710069 , PR China . Email: chenfl@nwu.edu.cn.
Fulin ChenKey Laboratory of Resource Biology and Modern Biotechnology in Western China , Ministry of Education , Northwest University , 229 TaiBai North Road , Xi'an , Shaanxi Province 710069 , PR China . Email: chenfl@nwu.edu.cn.
Shengyong ZhangMinistry of Education Key Laboratory of Synthetic and Natural Functional Molecule Chemistry , College of Chemistry & Materials Science , Northwest University , Xi'an , Shaanxi 710127 , PR China . Email: lijianli@nwu.edu.cn.
Jianli LiMinistry of Education Key Laboratory of Synthetic and Natural Functional Molecule Chemistry , College of Chemistry & Materials Science , Northwest University , Xi'an , Shaanxi 710127 , PR China . Email: lijianli@nwu.edu.cn.ORCID 0000-0002-4853-7961
Ministry of Education of the People's Republic of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glutathione (GSH) plays an important role in the body's biochemical defense system, and the detection of GSH in a physiological system is an important tool for understanding redox homeostasis. Protection-deprotection strategies have proven to be the most reliable, among existing detection methods. However, the understanding of how various electronic and steric effects influence a probe's ability to recognize a substrate is still lacking. In this study, we have analyzed various substituent effects on a GSH probe template

Identifiers

PMID30542554
PMCPMC6249757
OpenAlexW2893181160

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.