Evidence map›Paper›PMID 30542550›Full record

ArticleChemical science2018

Electron transfer ferredoxins with unusual cluster binding motifs support secondary metabolism in many bacteria.

Stella A Child, Justin M Bradley, Tara L Pukala, Dimitri A Svistunenko, Nick E Le Brun, Stephen G Bell

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 40 citations in OpenAlex.

  1. Mycobacteriumabscessus CYP123 is a steroid hydroxylase with an implication in host infection.Drug metabolism and disposition: the biological fate of chemicals · 2025
    Article
  2. Reversible enzyme-catalysed NADChemical science · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Contrasting Health Effects ofInternational journal of molecular sciences · 2022
    Article
  11. Structural insights into 3Fe-4S ferredoxins diversity inFrontiers in molecular biosciences · 2022
    Article
  12. Diversification of Ferredoxins across Living Organisms.Current issues in molecular biology · 2021
    Article
  13. Article
  14. Native Mass Spectrometry of Iron-Sulfur Proteins.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  15. Structural insights into the role of the acid-alcohol pair of residues required for dioxygen activation in cytochrome P450 enzymes.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2020
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Stella A ChildDepartment of Chemistry , University of Adelaide , SA 5005 , Australia . Email: stephen.bell@adelaide.edu.au.ORCID 0000-0002-7130-9676
Justin M BradleyCentre for Molecular and Structural Biochemistry , School of Chemistry , University of East Anglia , Norwich Research Park , Norwich , NR4 7TJ , UK.ORCID 0000-0003-1635-4455
Tara L PukalaDepartment of Chemistry , University of Adelaide , SA 5005 , Australia . Email: stephen.bell@adelaide.edu.au.ORCID 0000-0001-7391-1436
Dimitri A SvistunenkoSchool of Biological Sciences , University of Essex , Wivenhoe Park , Colchester CO4 3SQ , UK.ORCID 0000-0001-8060-2738
Nick E Le BrunCentre for Molecular and Structural Biochemistry , School of Chemistry , University of East Anglia , Norwich Research Park , Norwich , NR4 7TJ , UK.ORCID 0000-0001-9780-4061
Stephen G BellDepartment of Chemistry , University of Adelaide , SA 5005 , Australia . Email: stephen.bell@adelaide.edu.au.ORCID 0000-0002-7457-9727
The University of Adelaide · AUUniversity of East Anglia · GBUniversity of Essex · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The proteins responsible for controlling electron transfer in bacterial secondary metabolism are not always known or characterised. Here we demonstrate that many bacteria contain a set of unfamiliar ferredoxin encoding genes which are associated with those of cytochrome P450 (CYP) monooxygenases and as such are involved in anabolic and catabolic metabolism. The model organism

Identifiers

PMID30542550
PMCPMC6237146
OpenAlexW2888208256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.