Evidence map›Paper›PMID 30542533›Full record

ArticleMedChemComm2018

Novel tricyclic glycal-based

Marek M Nagiec, Jeremy R Duvall, Adam P Skepner, Eleanor A Howe, Jessica Bastien, Eamon Comer, Jean-Charles Marie, Stephen E Johnston, Joseph Negri, Michelle Eichhorn and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedChemComm, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Marek M NagiecTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.ORCID 0000-0003-1295-6141
Jeremy R DuvallTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.
Adam P SkepnerTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.
Eleanor A HoweTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.
Jessica BastienTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.
Eamon ComerTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.
Jean-Charles MarieTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.
Stephen E JohnstonTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.ORCID 0000-0002-1041-2530
Joseph NegriTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.
Michelle EichhornTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.
Julien VantouroutTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.
Clary ClishMetabolite Profiling Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA.
Kiran MusunuruDepartment of Stem Cell and Regenerative Biology , Harvard University , Cambridge , MA 02138 , USA.
Michael FoleyTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.
Jose R PerezTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.
Michelle A J PalmerTherapeutics Platform , Broad Institute of MIT and Harvard , Cambridge , MA02142 , USA . Email: marek@broadinstitute.org ; Tel: +1 617 714 7377.
Broad Institute · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased expression of the Tribbles pseudokinase 1 gene (

Identifiers

PMID30542533
PMCPMC6247893
OpenAlexW2890685481

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.