ReviewMedChemComm2018
Benzophenone: a ubiquitous scaffold in medicinal chemistry.
Review in MedChemComm, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Valorization of Agave potatorum byproducts as a source of volatile α-glucosidase inhibitors.Journal of the science of food and agriculture · 2026Article
- Analysis of Organic Residues on Neolithic Pottery in Different Settlements in Poland.Molecules (Basel, Switzerland) · 2026Article
- Recent Overview on the Molecular Hybrids Integrated With Benzosuberone/Benzo[7]annulene Derivatives as Multi-Target Therapeutics.Archiv der Pharmazie · 2026Review
- Extract of endophytic fungus Cepalotheca foveolata (N11) inhibits lytic bacteriophage: a study on activity, cytotoxicity, and chemical profiling.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Low-Temperature and High-Pressure Phase Transitions in Two 2‑Amino-4'-halobenzophenones: Incommensurate Modulation and a Case of Temperature-Induced Twinning.Crystal growth & design · 2026Article
- From Discovery to Clinical Trial: YCT-529, an Oral NonHormonal Male Contraceptive Targeting the Retinoic Acid Receptor Alpha.Journal of medicinal chemistry · 2026Article
- Article
- Synthesis, characterization, docking, MD simulation, and evaluation of antiproliferative effectiveness of new 4-aminobenzophenone derivatives.Journal of computer-aided molecular design · 2025Article
- Square planarRSC advances · 2025Article
- Novel Azo dyes containing a hydrazide-hydrazone moiety for dyeing polyester fabric.Scientific reports · 2025Article
- Advances in Cysteine Protease B Inhibitors for Leishmaniasis Treatment.Current drug targets · 2025Review
- Efficacy and safety of guttiferone E in melanoma-bearing mice.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
- Synthesis and bioactivity investigation of benzophenone and its derivatives.RSC advances · 2024Article
- A surface-independent bioglue using photo-crosslinkable benzophenone moiety.RSC advances · 2024Article
- Antioxidant, Anti-Diabetic, and Anti-Inflammation Activity ofInternational journal of molecular sciences · 2024Article
- A review of sources, pathways, and toxic effects of human exposure to benzophenone ultraviolet light filters.Eco-Environment & Health · 2024Review
- Carneusones A-F, Benzophenone Derivatives from Sponge-Derived FungusMarine drugs · 2024Article
- C-F bond activation enables synthesis of aryl difluoromethyl bicyclopentanes as benzophenone-type bioisosteres.Nature communications · 2024Article
- Benzophenones-natural metabolites with great Hopes in drug discovery: structures, occurrence, bioactivities, and biosynthesis.RSC advances · 2023Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The benzophenone scaffold represents a ubiquitous structure in medicinal chemistry because it is found in several naturally occurring molecules which exhibit a variety of biological activities, such as anticancer, anti-inflammatory, antimicrobial, and antiviral. In addition, various synthetic benzophenone motifs are present in marketed drugs. They also represent important ingredients in perfumes and can act as photoinitiators. This review will provide an overview of benzophenone moieties with medicinal aspects synthesized in the last 15 years and will cover the most potent molecule in each report. In this review, only benzophenones with substitutions on their aryl rings,
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.