Evidence map›Paper›PMID 30542492›Full record

ArticleExperimental and therapeutic medicine2018

miR-148b-3p, miR-337-5p and miR-423-5p expression in alveolar ridge atrophy and their roles in the proliferation and apoptosis of OMMSCs.

Sefei Yang, Jun Guo, Lei Zhou, Helin Xing, Xianli Wang, Chaofang Dong

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. miR-423 sponged by lncRNA NORHA inhibits granulosa cell apoptosis.Journal of animal science and biotechnology · 2023
    Article
  3. Article
  4. Circulating miRNAs associated with bone mineral density in healthy adult baboons.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Sefei YangDepartment of Stomatology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Jun GuoDepartment of Stomatology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Lei ZhouDepartment of Stomatology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Helin XingDepartment of Prosthodontics, School of Stomatology, Capital Medical University, Beijing 100050, P.R. China.
Xianli WangDepartment of Prosthodontics, Anyang Sixth People's Hospital, Anyang, Henan 455000, P.R. China.
Chaofang DongLab for Corrosion Control and Research Development, School of Mathematics and Physics, University of Science and Technology Beijing, Beijing 100853, P.R. China.
Chinese PLA General Hospital · CNCapital Medical University · CNThe Fifth People's Hospital of Anyang · CNUniversity of Science and Technology Beijing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs/miRs) have key roles in various physiological and pathological processes by regulating the expression of specific genes. The identification of miRNAs involved in bone metabolism may provide insight into the expression of genes associated with the development of alveolar ridge atrophy. In the present study, the miRNA expression profiles in alveolar ridge atrophy and normal tissue samples were investigated by miRNA microarray analysis. Among the 52 differentially expressed miRNAs identified, the expression levels of 20 selected miRNAs in the alveolar ridge atrophy and normal tissue samples were verified by reverse transcription-quantitative polymerase chain reaction. The results indicated that the expression levels of 11 miRNAs were significantly different between alveolar ridge atrophy and normal tissue samples; however, only three of them (miR-148b-3p, miR-337-5p and miR-423-5p) were previously reported to be involved in bone metabolism.

Indexed as

alveolar ridge atrophyapoptosisbone marrow mesenchymal stem cellsmiRNAproliferation

Identifiers

PMID30542492
PMCPMC6257774
OpenAlexW2897159116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.