Evidence map›Paper›PMID 30542486›Full record

ArticleExperimental and therapeutic medicine2018

Atorvastatin reverses the dysfunction of human umbilical vein endothelial cells induced by angiotensin II.

Haiming Dang, Bangrong Song, Ran Dong, Hongjia Zhang

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Haiming DangDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Chaoyang, Beijing 100029, P.R. China.
Bangrong SongDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Chaoyang, Beijing 100029, P.R. China.
Ran DongDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Chaoyang, Beijing 100029, P.R. China.
Hongjia ZhangDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Chaoyang, Beijing 100029, P.R. China.
Beijing Anzhen Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Statins exert pleiotropic effects on endothelial cells, in addition to lowering cholesterol. This study evaluated angiotensin II (Ang II)-induced dysfunction in human umbilical vein endothelial cells (HUVECs), and the effects of atorvastatin (Ator) on induced HUVECs

Indexed as

atorvastatincellular dysfunctionhomeostasishuman umbilical vein endothelial cells

Identifiers

PMID30542486
PMCPMC6257519
OpenAlexW2897548277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.