Evidence map›Paper›PMID 30542453›Full record

ArticleExperimental and therapeutic medicine2018

Endothelial PAS domain protein 1 gene hypomethylation is associated with colorectal cancer in Han Chinese.

Ranran Pan, Cong Zhou, Jie Dai, Xiuru Ying, Hang Yu, Jie Zhong, Yihan Zhang, Boyi Wu, Yiyi Mao, Dongping Wu and 3 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  5. International journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Ranran PanMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Cong ZhouMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Jie DaiMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Xiuru YingMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Hang YuMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Jie ZhongMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Yihan ZhangMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Boyi WuMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Yiyi MaoMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Dongping WuDepartment of Medical Oncology, Shaoxing People's Hospital, Shaoxing, Zhejiang 312000, P.R. China.
Jieer YingDepartment of Medical Oncology, Zhejiang Cancer Hospital, Hangzhou, Zhejiang 310022, P.R. China.
Wei ZhangDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Shiwei DuanMedical Genetics Center, School of Medicine, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.
Ningbo University · CNNorthwestern University · USShaoxing People's Hospital · CNZhejiang Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial PAS domain-containing protein 1 (EPAS1) serves a role in angiogenesis, which is important for the development of tumors, including colorectal cancer (CRC). The current study aimed to estimate whether

Indexed as

colorectal cancerDNA methylationendothelial PAS domain-containing protein 1quantitative methylation-specific polymerase chain reaction

Identifiers

PMID30542453
PMCPMC6257466
OpenAlexW2897188629

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.