Evidence map›Paper›PMID 30542351›Full record

ArticleFrontiers in immunology2018

A Highly Active Form of XCL1/Lymphotactin Functions as an Effective Adjuvant to Recruit Cross-Presenting Dendritic Cells for Induction of Effector and Memory CD8

Kazuhiko Matsuo, Kosuke Kitahata, Fumika Kawabata, Momo Kamei, Yuta Hara, Shiki Takamura, Naoki Oiso, Akira Kawada, Osamu Yoshie, Takashi Nakayama

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Evaluation of Immunoprotective Effects of DNA Vaccine Based onAnimals : an open access journal from MDPI · 2026
    Article
  4. Natural and Engineered Cytokines as Cancer Therapeutics.Annual review of cancer biology · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Cytotoxic T Cells: Kill, Memorize, and Mask to Maintain Immune Homeostasis.International journal of molecular sciences · 2025
    Review
  9. Synergistic Enhancement ofAnimals : an open access journal from MDPI · 2025
    Article
  10. Review
  11. The multifaceted role of XCL1 in health and disease.Protein science : a publication of the Protein Society · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. LAG-3xPD-L1 bispecific antibody potentiates antitumor responses of T cells through dendritic cell activation.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kazuhiko MatsuoDivision of Chemotherapy, Kindai University Faculty of Pharmacy, Osaka, Japan.
Kosuke KitahataDivision of Chemotherapy, Kindai University Faculty of Pharmacy, Osaka, Japan.
Fumika KawabataDivision of Chemotherapy, Kindai University Faculty of Pharmacy, Osaka, Japan.
Momo KameiDivision of Chemotherapy, Kindai University Faculty of Pharmacy, Osaka, Japan.
Yuta HaraLaboratory of Cell Biology, Kindai University Faculty of Pharmacy, Osaka, Japan.
Shiki TakamuraDepartment of Immunology, Kindai University Faculty of Medicine, Osaka, Japan.
Naoki OisoDepartment of Dermatology, Kindai University Faculty of Medicine, Osaka, Japan.
Akira KawadaDepartment of Dermatology, Kindai University Faculty of Medicine, Osaka, Japan.
Osamu YoshieKindai University, Osaka, Japan.
Takashi NakayamaDivision of Chemotherapy, Kindai University Faculty of Pharmacy, Osaka, Japan.
Kindai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The chemokine receptor XCR1 is known to be selectively expressed by cross-presenting dendritic cells (DCs), while its ligand XCL1/lymphotactin is mainly produced by activated CD8

Indexed as

Adjuvants, ImmunologicAnimalsAntigensAntigens, CDCalciumCD8-Positive T-LymphocytesCell LineChemokines, CCross-PrimingDendritic CellsImmunologic MemoryIntegrin alpha ChainsKiller Cells, NaturalLymphokinesMiceMice, Inbred C57BLAdjuvants, Immunologicalpha E integrinsAntigensAntigens, CDCalciumChemokines, CIntegrin alpha ChainsLymphokineslymphotactinOvalbuminSialoglycoproteinsXcl1 protein, mouseadjuvantcross-presenting DCCTLXCL1XCR1

Identifiers

PMID30542351
PMCPMC6277777
OpenAlexW2902374890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.