Evidence map›Paper›PMID 30542281›Full record

ArticleFrontiers in pharmacology2018

Study of the Tissue Distribution of TLQP-21 in Mice Using [

Elia A Turolla, Silvia Valtorta, Elena Bresciani, Jean-Alain Fehrentz, Liliana Giuliano, Stefano Stucchi, Sara Belloli, Paolo Rainone, Francesco Sudati, Laura Rizzi and 6 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. The molecular identity of the TLQP-21 peptide receptor.Cellular and molecular life sciences : CMLS · 2021
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Elia A TurollaSchool of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Silvia ValtortaSchool of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Elena BrescianiSchool of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Jean-Alain FehrentzInstitute of Biomolécules Max Mousseron, University of Montpellier, CNRS, ENSCM, School of Pharmacy, Montpellier, France.
Liliana GiulianoSchool of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Stefano StucchiSchool of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Sara BelloliNational Research Council, Institute of Molecular Bioimaging and Physiology, Milan, Italy.
Paolo RainoneNuclear Medicine Department, San Raffaele Scientific Institute, Milan, Italy.
Francesco SudatiNuclear Medicine Department, San Raffaele Scientific Institute, Milan, Italy.
Laura RizziSchool of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Laura MolteniSchool of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Pascal VerdièInstitute of Biomolécules Max Mousseron, University of Montpellier, CNRS, ENSCM, School of Pharmacy, Montpellier, France.
Jean MartinezInstitute of Biomolécules Max Mousseron, University of Montpellier, CNRS, ENSCM, School of Pharmacy, Montpellier, France.
Antonio TorselloSchool of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Rosa Maria MorescoSchool of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Sergio ToddeSchool of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TLQP-21 is a neuropeptide that is involved in the control of several physiological functions, including energy homeostasis. Since TLQP-21 could oppose the early phase of diet-induced obesity, it has raised a huge interest, but very little is known about its mechanisms of action on peripheral tissues. Our aim was to investigate TLQP-21 distribution in brain and peripheral tissues after systemic administration using positron emission tomography. We report here the radiolabeling of NODA-methyl phenylacetic acid (MPAA) functionalized JMV5763, a short analog of TLQP-21, with [

Indexed as

biodistributionfluorine-18obesityPETradiolabelingTLQP-21VGF

Identifiers

PMID30542281
PMCPMC6277862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.