ArticleJournal of biosciences2018
Alterations in gut bacterial and fungal microbiomes are associated with bacterial Keratitis, an inflammatory disease of the human eye.
Article in Journal of biosciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Clinical trials targeting the gut-microbiome to effect ocular health: a systematic review.Eye (London, England) · 2023Pooled it
- A systematic review of gut microbiome and ocular inflammatory diseases: Are they associated?Indian journal of ophthalmology · 2021Pooled it
- Associations and interactions between prokaryotes and other gut biota in non-human primates.Primates; journal of primatology · 2026Review
- Role of gut microbiomes in different ocular pathologies: A systematic review.World journal of gastrointestinal pathophysiology · 2025Article
- The Gut Mycobiome for Precision Medicine.Journal of fungi (Basel, Switzerland) · 2025Review
- Tailoring the natural rare sugars D-tagatose and L-sorbose to produce novel functional carbohydrates.NPJ science of food · 2024Article
- Evaluation of the Crosstalk Between the Host Mycobiome and Bacteriome in Patients with Chronic Pancreatitis.Indian journal of microbiology · 2024Article
- Gut Microbiota Profiles in Myopes and Nonmyopes.Investigative ophthalmology & visual science · 2024Article
- Fecal microbiota transplantation for glaucoma; a potential emerging treatment strategy.Current research in microbial sciences · 2024Review
- Association of Gut Microbiota with Age-Related Macular Degeneration and Glaucoma: A Bidirectional Mendelian Randomization Study.Nutrients · 2023Article
- Intraocular Microbiome in Diabetes and Diabetic Retinopathy: A Pilot Study.Ophthalmology and therapy · 2023Article
- The gut-retina axis: a new perspective in the prevention and treatment of diabetic retinopathy.Frontiers in endocrinology · 2023Review
- Gut microbiota and eye diseases: a bibliometric study and visualization analysis.Frontiers in cellular and infection microbiology · 2023Article
- More than Antibiotics: Latest Therapeutics in the Treatment and Prevention of Ocular Surface Infections.Journal of clinical medicine · 2022Review
- Evidence Suggesting the Role of Gut Dysbiosis in Diabetic Retinopathy.Investigative ophthalmology & visual science · 2022Review
- Mucosal immunology of the ocular surface.Mucosal immunology · 2022Review
- Do Oral Pathogens Inhabit the Eye and Play a Role in Ocular Diseases?Journal of clinical medicine · 2022Review
- Characterization of Conjunctival Sac Microbiome from Patients with Allergic Conjunctivitis.Journal of clinical medicine · 2022Article
- Gut mycobiome dysbiosis in rats showing retinal changes indicative of diabetic retinopathy.PloS one · 2022Article
- Mycobiomes of the Ocular Surface in Bacterial Keratitis Patients.Frontiers in ophthalmology · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dysbiosis, or imbalance in the gut microbiome, has been implicated in auto-immune, inflammatory, neurological diseases as well as in cancers. More recently it has also been shown to be associated with ocular diseases. In the present study, the association of gut microbiome dysbiosis with bacterial Keratitis, an inflammatory eye disease which significantly contributes to corneal blindness, was investigated. Bacterial and fungal gut microbiomes were analysed using fecal samples of healthy controls (HC, n = 21) and bacterial Keratitis patients (BK, n = 19). An increase in abundance of several antiinflammatory organisms including
Indexed as
Identifiers
30541945W2895324985What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.