Evidence map›Paper›PMID 30541934›Full record

ArticleJournal of clinical microbiology2019

Impact of Rapid Molecular Diagnostic Testing of Respiratory Viruses on Outcomes of Adults Hospitalized with Respiratory Illness: a Multicenter Quasi-experimental Study.

Nasir Wabe, Ling Li, Robert Lindeman, Ruth Yimsung, Maria R Dahm, Susan McLennan, Kate Clezy, Johanna I Westbrook, Andrew Georgiou

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Guidelines for Antibiotics Prescription in Critically Ill Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Evaluation of Panbio rapid antigen test for SARS-CoV-2 in symptomatic patients and their contacts: a multicenter study.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Cepheid XpertInfluenza and other respiratory viruses · 2021
    Article
  19. Molecular Testing for Acute Respiratory Tract Infections: Clinical and Diagnostic Recommendations From the IDSA's Diagnostics Committee.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Nasir WabeCentre for Health Systems and Safety Research, Australian Institute of Health Innovation, Macquarie University, North Ryde, NSW, Australia nasir.wabe@mq.edu.au.ORCID 0000-0002-9740-6319
Ling LiCentre for Health Systems and Safety Research, Australian Institute of Health Innovation, Macquarie University, North Ryde, NSW, Australia.
Robert LindemanNSW Health Pathology, Chatswood, NSW, Australia.
Ruth YimsungNSW Health Pathology, Chatswood, NSW, Australia.
Maria R DahmCentre for Health Systems and Safety Research, Australian Institute of Health Innovation, Macquarie University, North Ryde, NSW, Australia.
Susan McLennanNSW Health Pathology, Chatswood, NSW, Australia.
Kate ClezyInfectious Diseases Department, Prince of Wales Hospital, Randwick, NSW, Australia.
Johanna I WestbrookCentre for Health Systems and Safety Research, Australian Institute of Health Innovation, Macquarie University, North Ryde, NSW, Australia.
Andrew GeorgiouCentre for Health Systems and Safety Research, Australian Institute of Health Innovation, Macquarie University, North Ryde, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A standard multiplex PCR offers comprehensive testing for respiratory viruses. However, it has traditionally been performed in a referral laboratory with a lengthy turnaround time, which can reduce patient flow through the hospital. We aimed to determine whether the introduction of a rapid PCR, but with limited targets (Cepheid Xpert Flu/RSV XC), was associated with improved outcomes for adults hospitalized with respiratory illness. A controlled quasi-experimental study was conducted across three hospitals in New South Wales, Australia. Intervention groups received standard multiplex PCR during the preimplementation, July to December 2016 (

Indexed as

AgedAged, 80 and overFemaleHealth ResourcesHospitalizationHumansInfluenza, HumanLength of StayMaleMiddle AgedMolecular Diagnostic TechniquesMultiplex Polymerase Chain ReactionNew South WalesPoint-of-Care SystemsRespiratory Syncytial Virus InfectionsRespiratory Tract Infectionsinfluenzamolecular diagnosticrapid PCRrespiratory viruses

Identifiers

PMID30541934
PMCPMC6440765

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.