Evidence map›Paper›PMID 30541898›Full record

ArticleBioscience reports2019

Bronchial epithelial cells of young and old mice directly regulate the differentiation of Th2 and Th17.

Da Liu, Long He, Ning Ding, Wenjin Sun, Lulu Qiu, Li Xu, Aijun Jia, Cong Peng, Dongshan Zhang, Xudong Xiang

Open access · goldAbstract readComparative Study
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Da LiuThe Second Xiangya Hospital of Central South University, Changsha, Hunan Province 410011, China.
Long HeDepartment of Clinical Laboratory, Puai Hospital, Tongji Medical College, Huazhong University of Sciences and Technology, Wuhan, Hubei Province 430030, China.
Ning DingDepartment of Emergency, Changsha Central Hospital, Changsha, Hunan Province 410004, China.
Wenjin SunThe Second Xiangya Hospital of Central South University, Changsha, Hunan Province 410011, China.
Lulu QiuThe Second Xiangya Hospital of Central South University, Changsha, Hunan Province 410011, China.
Li XuThe Second Xiangya Hospital of Central South University, Changsha, Hunan Province 410011, China.
Aijun JiaThe Second Xiangya Hospital of Central South University, Changsha, Hunan Province 410011, China.
Cong PengThe Second Xiangya Hospital of Central South University, Changsha, Hunan Province 410011, China.
Dongshan ZhangThe Second Xiangya Hospital of Central South University, Changsha, Hunan Province 410011, China.
Xudong XiangThe Second Xiangya Hospital of Central South University, Changsha, Hunan Province 410011, China xudongx_99@outlook.com.ORCID 0000-0003-4043-4009
Central South University · CNChangsha Central Hospital · CNHuazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To determine whether or not house dust mite (HDM) and HDM+lipopolysaccharide (LPS) exposure causes a difference in T-cell subsets from young and old mice. The bronchial epithelial cells (BECs) from young and old mice were divided into three groups (PBS (control), HDM, and HDM+LPS). CD4

Indexed as

Age FactorsAnimalsAsthmaBronchiCD4-Positive T-LymphocytesCell DifferentiationCells, CulturedEpithelial CellsGATA3 Transcription FactorLipopolysaccharidesMaleMice, Inbred C57BLNuclear Receptor Subfamily 1, Group F, Member 3PyroglyphidaeTh17 CellsTh2 CellsGata3 protein, mouseGATA3 Transcription FactorLipopolysaccharidesNuclear Receptor Subfamily 1, Group F, Member 3Rorc protein, mouseasthmaepithelial cellsTh17 cellsTh2 cells

Identifiers

PMID30541898
PMCPMC6356035
OpenAlexW2905250717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.