Evidence map›Paper›PMID 30541854›Full record

ArticleJournal of virology2019

The Frequency of Vaccine-Induced T-Cell Responses Does Not Predict the Rate of Acquisition after Repeated Intrarectal SIVmac239 Challenges in

Mauricio A Martins, Lucas Gonzalez-Nieto, Young C Shin, Aline Domingues, Martin J Gutman, Helen S Maxwell, Diogo M Magnani, Michael J Ricciardi, Núria Pedreño-Lopez, Varian K Bailey and 9 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Env-independent protection of intrarectal SIV challenge by vaccine induction of Gag/Vif-specific CD8Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Article
  5. Article
  6. Article
  7. Rhesus Cytomegalovirus-Specific CD8Frontiers in immunology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 1 country.

Mauricio A MartinsDepartment of Pathology, University of Miami, Miami, Florida, USA mmartins@med.miami.edu.ORCID 0000-0001-8336-216X
Lucas Gonzalez-NietoDepartment of Pathology, University of Miami, Miami, Florida, USA.
Young C ShinDepartment of Pathology, University of Miami, Miami, Florida, USA.
Aline DominguesDepartment of Pathology, University of Miami, Miami, Florida, USA.
Martin J GutmanDepartment of Pathology, University of Miami, Miami, Florida, USA.
Helen S MaxwellDepartment of Pathology, University of Miami, Miami, Florida, USA.
Diogo M MagnaniDepartment of Pathology, University of Miami, Miami, Florida, USA.
Michael J RicciardiDepartment of Pathology, University of Miami, Miami, Florida, USA.
Núria Pedreño-LopezDepartment of Pathology, University of Miami, Miami, Florida, USA.
Varian K BaileyDepartment of Pathology, University of Miami, Miami, Florida, USA.
John D AltmanDepartment of Microbiology and Immunology, Emory University, Atlanta, Georgia, USA.
Christopher L ParksInternational AIDS Vaccine Initiative, AIDS Vaccine Design and Development Laboratory, Brooklyn, New York, USA.
David B AllisonSchool of Public Health, Indiana University-Bloomington, Bloomington, Indiana, USA.
Keisuke EjimaSchool of Public Health, Indiana University-Bloomington, Bloomington, Indiana, USA.
Eva G RakaszWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Saverio CapuanoWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Ronald C DesrosiersDepartment of Pathology, University of Miami, Miami, Florida, USA.ORCID 0000-0001-6851-3003
Jeffrey D LifsonAIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
David I WatkinsDepartment of Pathology, University of Miami, Miami, Florida, USA.
University of Miami · USIndiana University Bloomington · USUniversity of Wisconsin–Madison · USEmory University · USInternational AIDS Vaccine Initiative · USLeidos (United States) · US

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALLAN E RODRIGUEZ · 2007 to 2026
$33.8M
The Functional Significance of CTL EscapeR37AI052056 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI WATKINS, DAVID I · 2008 to 2017
$7.1M
Gamma-2 Herpesviruses as Vaccine Vectors for AIDSR37AI063928 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI DESROSIERS, RONALD C · 2013 to 2022
$5.1M
Gamma-2 Herpesviruses as Vaccine Vectors for AIDSR01AI063928 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI DESROSIERS, RONALD C · 2005 to 2013
$2.9M
Can vaccine-induced CD8 T cells prevent chronic phase AIDS virus replication?R01AI108421 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI WATKINS, DAVID I · 2014 to 2018
$2.9M
Ipilimumab as an adjuvant for HIV vaccinesK01OD023032 · OD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MARTINS, MAURICIO DE AGUIAR · 2016 to 2018
$993k
CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001ENIAID NIH HHS P30 AI073961NIAID NIH HHS R01 AI063928NIAID NIH HHS R01 AI108421NIAID NIH HHS R37 AI052056NIAID NIH HHS R37 AI063928NIH HHS K01 OD023032NIH HHS P51 OD011106
6 · The paper itself

Abstract

Approximately 50% of rhesus macaques (RMs) expressing the major histocompatibility complex class I (MHC-I) allele

Indexed as

AnimalsCD8-Positive T-LymphocytesEpitopes, T-LymphocyteGene Products, nefGene Products, vifHistocompatibility Antigens Class IMacaca mulattaSAIDS VaccinesSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusVaccinationViral VaccinesViremiaEpitopes, T-LymphocyteGene Products, nefGene Products, vifHistocompatibility Antigens Class ISAIDS VaccinesViral Vaccineshuman immunodeficiency virussimian immunodeficiency virusvaccines

Identifiers

PMID30541854
PMCPMC6384082
OpenAlexW2904083059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.