Evidence map›Paper›PMID 30541853›Full record

ArticleJournal of virology2019

HIV Infection Functionally Impairs Mycobacterium tuberculosis-Specific CD4 and CD8 T-Cell Responses.

Patrizia Amelio, Damien Portevin, Jerry Hella, Klaus Reither, Lujeko Kamwela, Omar Lweno, Anneth Tumbo, Linda Geoffrey, Khalid Ohmiti, Song Ding and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

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  20. Memory stem CD8Frontiers in cellular and infection microbiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Patrizia AmelioService of Immunology and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Damien PortevinSwiss Tropical and Public Health Institute, Basel, Switzerland.
Jerry HellaIfakara Health Institute, Bagamoyo, Tanzania.
Klaus ReitherSwiss Tropical and Public Health Institute, Basel, Switzerland.
Lujeko KamwelaIfakara Health Institute, Bagamoyo, Tanzania.
Omar LwenoIfakara Health Institute, Bagamoyo, Tanzania.
Anneth TumboSwiss Tropical and Public Health Institute, Basel, Switzerland.
Linda GeoffreySwiss Tropical and Public Health Institute, Basel, Switzerland.
Khalid OhmitiService of Immunology and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Song DingEuroVacc Foundation, Lausanne, Switzerland.
Giuseppe PantaleoService of Immunology and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland.
Claudia Daubenberger *Swiss Tropical and Public Health Institute, Basel, Switzerland.
Matthieu Perreau *Service of Immunology and Allergy, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland Matthieu.Perreau@chuv.ch.
Ifakara Health Institute · TZUniversity of Lausanne · CHUniversity of Basel · CHEurovacc Foundation · CHSwiss Tropical and Public Health Institute · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human immunodeficiency virus (HIV) infection is the major risk factor predisposing for

Indexed as

AdultCD4 Lymphocyte CountCD8-Positive T-LymphocytesCoinfectionC-Reactive ProteinCytokinesFemaleGATA3 Transcription FactorHIV-1HIV InfectionsHumansLatent TuberculosisMaleMycobacterium tuberculosisProgrammed Cell Death 1 ReceptorTh2 CellsC-Reactive ProteinCytokinesGATA3 Transcription FactorPDCD1 protein, humanProgrammed Cell Death 1 ReceptorCD4 T cellsexhaustionHIVMycobacterium tuberculosis

Identifiers

PMID30541853
PMCPMC6384080
OpenAlexW2904701318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.