Evidence map›Paper›PMID 30541848›Full record

ArticleJournal of virology2019

Contrasting Roles of the PD-1 Signaling Pathway in Dendritic Cell-Mediated Induction and Regulation of HIV-1-Specific Effector T Cell Functions.

Tatiana M Garcia-Bates, Mariana L Palma, Chengli Shen, Andrea Gambotto, Bernard J C Macatangay, Robert L Ferris, Charles R Rinaldo, Robbie B Mailliard

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  7. World journal of gastroenterology · 2022
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Lentiviral-Vector-Based Dendritic Cell Vaccine Synergizes with Checkpoint Blockade to Clear Chronic Viral Infection.Molecular therapy : the journal of the American Society of Gene Therapy · 2020
    Article
  14. Article
  15. Review
  16. Review
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  18. The PD-1/PD-L1 Axis and Virus Infections: A Delicate Balance.Frontiers in cellular and infection microbiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tatiana M Garcia-BatesDepartment of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA tgarcia@pitt.edu.ORCID 0000-0001-7579-5272
Mariana L PalmaDepartment of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA.
Chengli ShenDepartment of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Andrea GambottoDepartment of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Bernard J C MacatangayDepartment of Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Robert L FerrisDepartment of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Charles R RinaldoDepartment of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA.
Robbie B MailliardDepartment of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA.
University of Pittsburgh · US

Funding

University of Pittsburgh Multicenter AIDS Cohort Study (MACS)U01AI035041 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MARTINSON, JEREMY JAMES, RINALDO, CHARLES R · 1993 to 2018
$71.4M
Programming Dendritic Cells to Expose the Persistent HIV-1 Latent Reservoir for Immune TargetingR21AI131763 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MAILLIARD, ROBBIE B · 2017 to 2018
$429k
NIAID NIH HHS R21 AI131763NIAID NIH HHS U01 AI035041
6 · The paper itself

Abstract

Eliciting highly functional CD8

Indexed as

AdultB7-H1 AntigenCD40 LigandDendritic CellsHIV-1HIV InfectionsHumansImmune EvasionImmunologic MemoryInterleukin-12 Subunit p35Lymphocyte ActivationProgrammed Cell Death 1 ReceptorSignal TransductionT-Lymphocytes, CytotoxicT-Lymphocytes, Helper-InducerB7-H1 AntigenCD274 protein, humanCD40 LigandIL12A protein, humanInterleukin-12 Subunit p35PDCD1 protein, humanProgrammed Cell Death 1 Receptorhuman immunodeficiency virusPD-1T cell immunityT lymphocytes

Identifiers

PMID30541848
PMCPMC6384070
OpenAlexW2905108465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.