Evidence map›Paper›PMID 30541840›Full record

ArticleJournal of virology2019

Role of Sphingomyelin in Alphaherpesvirus Entry.

Gabrielle Pastenkos, Jonathan L Miller, Suzanne M Pritchard, Anthony V Nicola

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. HIV and SIV Envelope Glycoproteins Interact with Glycolipids and Lipids.International journal of molecular sciences · 2023
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Membrane Rafts: Portals for Viral Entry.Frontiers in microbiology · 2021
    Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gabrielle PastenkosDepartment of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Jonathan L MillerDepartment of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Suzanne M PritchardDepartment of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Anthony V NicolaDepartment of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA anthony.nicola@wsu.edu.
Washington State University · US

Funding

Infectious Diseases and Microbial Immunology Training ProgramT32AI007025 · NIAID · WASHINGTON STATE UNIVERSITY · PI Thomas H KAWULA, M KARIUKI NJENGA · 1985 to 2026
$7.4M
Low pH-mediated HSV fusion and entryR01AI119159 · NIAID · WASHINGTON STATE UNIVERSITY · PI NICOLA, ANTHONY V · 2015 to 2019
$2.0M
Viral and cellular mechanisms of HSV fusion and entryR56AI119159 · NIAID · WASHINGTON STATE UNIVERSITY · PI NICOLA, ANTHONY V · 2022 to 2022
$374k
NIAID NIH HHS R01 AI119159NIAID NIH HHS R56 AI119159NIAID NIH HHS T32 AI007025
6 · The paper itself

Abstract

Bovine herpesvirus 1 (BoHV-1) is an alphaherpesvirus that causes disease in cattle populations worldwide. Sphingomyelin (SM) is the most abundant sphingolipid in the mammalian cell membrane, where it preferentially associates with cholesterol to form lipid raft domains. SM is a substrate for the lysosome-resident enzyme acid sphingomyelinase, which plays a role in cell membrane repair following injury. Treatment of cells with noncytotoxic concentrations of

Indexed as

AmitriptylineAnimalsCattleCattle DiseasesCell LineChlorocebus aethiopsDogsHerpesvirus 1, BovineHerpesvirus 1, SuidImipramineMadin Darby Canine Kidney CellsMembrane MicrodomainsSphingomyelin PhosphodiesteraseSphingomyelinsVero CellsVirus InternalizationAmitriptylineImipramineSphingomyelin PhosphodiesteraseSphingomyelinsbovine herpesvirus 1endocytosisherpes simplex virusherpesvirusesmembranespseudorabies virussphingomyelinviral entry

Identifiers

PMID30541840
PMCPMC6384054
OpenAlexW2903850664

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.