Evidence map›Paper›PMID 30541835›Full record

ArticleJournal of virology2019

The Triticum Mosaic Virus Internal Ribosome Entry Site Relies on a Picornavirus-Like YX-AUG Motif To Designate the Preferred Translation Initiation Site and To Likely Target the 18S rRNA.

Helena Jaramillo-Mesa, Megan Gannon, Elijah Holshbach, Jincan Zhang, Robyn Roberts, Matthew Buettner, Aurélie M Rakotondrafara

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. MultipleFrontiers in plant science · 2022
    Article
  9. Review
  10. Translational gene regulation in plants: A green new deal.Wiley interdisciplinary reviews. RNA · 2020
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Helena Jaramillo-Mesa *Department of Plant Pathology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Megan Gannon *Department of Plant Pathology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Elijah HolshbachDepartment of Plant Pathology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Jincan ZhangDepartment of Plant Pathology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Robyn RobertsDepartment of Plant Pathology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Matthew BuettnerDepartment of Plant Pathology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Aurélie M RakotondrafaraDepartment of Plant Pathology, University of Wisconsin-Madison, Madison, Wisconsin, USA rakotondrafa@wisc.edu.
University of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several viruses encode an internal ribosome entry site (IRES) at the 5' end of their RNA, which, unlike most cellular mRNAs, initiates translation in the absence of a 5' m7GpppG cap. Here, we report a uniquely regulated translation enhancer found in the 739-nucelotide (nt) sequence of the Triticum mosaic virus (TriMV) leader sequence that distinguishes the preferred initiation site from a plethora of IRES-encoded AUG triplets. Through deletion mutations of the TriMV 5' untranslated region (UTR), we show that the TriMV 5' UTR encodes a

Indexed as

5' Untranslated RegionsCodon, InitiatorPeptide Chain Initiation, TranslationalPlant DiseasesPotyviridaeProtein BiosynthesisRibosomesRNA, Ribosomal, 18SRNA, ViralSequence DeletionTriticum5' Untranslated RegionsCodon, InitiatorRNA, Ribosomal, 18SRNA, Viral5′ UTRcap independentIRESplant viruspotyvirustranslationYX-AUG

Identifiers

PMID30541835
PMCPMC6384068
OpenAlexW2904008370

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.