ArticleOccupational and environmental medicine2019
Women's occupational exposure to polycyclic aromatic hydrocarbons and risk of breast cancer.
Article in Occupational and environmental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Relationship between particulate matter exposure and female breast cancer incidence and mortality: a systematic review and meta-analysis.International archives of occupational and environmental health · 2021Pooled it
- Environmental exposures and breast cancer risk in the context of underlying susceptibility: A systematic review of the epidemiological literature.Environmental research · 2020Pooled it
- An integrative analysis reveals the mechanism of plastic stabilizers inducing breast cancer.PLoS computational biology · 2026Article
- [Serum levels of polycyclic aromatic hydrocarbons and health risk assessment among children and adolescents].Se pu = Chinese journal of chromatography · 2025Article
- Occupational exposure to combustion by-products and breast cancer risk in postmenopausal women.Annals of work exposures and health · 2025Article
- Polycyclic aromatic hydrocarbons exposure as a potential risk factor for miscarriage among women in the United States: A secondary dataset analysis of NHANES data for the period 2005-2014.Tobacco induced diseases · 2025Article
- Personal history of irradiation and risk of breast cancer: A Mendelian randomisation study.Journal of global health · 2024Article
- Exposure to Metalworking Fluids and Cancer Incidence in the United Auto Workers-General Motors Cohort.American journal of epidemiology · 2023Article
- Investigating the Role of Glutathione S- Transferase Genes, Histopathological and Molecular Subtypes, Gene-Gene Interaction and Its Susceptibility to Breast Carcinoma in Ethnic North- Indian Population.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Interactions between exposure to polycyclic aromatic hydrocarbons and xenobiotic metabolism genes, and risk of breast cancer.Breast cancer (Tokyo, Japan) · 2022Article
- Environmental exposure and the role of AhR in the tumor microenvironment of breast cancer.Frontiers in pharmacology · 2022Review
- Joint effects of polycyclic aromatic hydrocarbons, smoking, and XPC polymorphisms on damage in exon 2 of KRAS gene among young coke oven workers.Frontiers in public health · 2022Article
- Women's health and night shift work: Potential targets for future strategies in breast cancer (Review).Biomedical reports · 2021Review
- Curcumin Suppresses the Lipid Accumulation and Oxidative Stress Induced by Benzo[a]pyrene Toxicity in HepG2 Cells.Antioxidants (Basel, Switzerland) · 2021Article
- Review
- Breast cancer and occupational exposures: an integrative review of the literature.Revista brasileira de medicina do trabalho : publicacao oficial da Associacao Nacional de Medicina do Trabalho-ANAMT · 2021Review
- Breast cancer among Danish women occupationally exposed to diesel exhaust and polycyclic aromatic hydrocarbons, 1964-2016.Scandinavian journal of work, environment & health · 2021Article
- Polycyclic Aromatic Hydrocarbons and Mammary Cancer Risk: Does Obesity Matter too?Journal of cancer immunology · 2021Article
- Elevated exposure to polycyclic aromatic hydrocarbons (PAHs) may trigger cancers in Pakistan: an environmental, occupational, and genetic perspective.Environmental science and pollution research international · 2020Review
- Therapeutic effect of Aegle marmelos fruit extract against DMBA induced breast cancer in rats.Scientific reports · 2020Article
Corrections and comments
- Commented on byResponse to Lee2019
Authors and funding
7 authors at 6 institutions in 2 countries.
Funding
Abstract
objectiveTo estimate the association between occupational polycyclic aromatic hydrocarbon (PAH) exposure and female breast cancer.
methodsLifetime work histories for 1130 cases and 1169 controls from British Columbia and Ontario (Canada) were assessed for PAH exposure using a job-exposure matrix based on compliance measurements obtained during US Occupational Safety and Health Administration workplace safety inspections.
resultsExposure to any level of PAHs was associated with an increased risk of breast cancer (OR=1.32, 95% CI: 1.10 to 1.59), as was duration at high PAH exposure (for >7.4 years: OR=1.45, 95% CI: 1.10 to 1.91; p
conclusionsOur study suggests that prolonged occupational exposure to PAH may increase breast cancer risk, especially among women with a family history of breast cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.