ArticleParasites & vectors2018
Differentiation of Trichinella species (Trichinella spiralis/Trichinella britovi versus Trichinella pseudospiralis) using western blot.
Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Global prevalence of Trichinella in pigs: A systematic review and meta-analysis.Veterinary medicine and science · 2022Pooled it
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- AxiWorm: a new tool using YOLOv5 to test antiparasitic drugs against Trichinella spiralis.Parasites & vectors · 2025Article
- Identification ofVeterinary research forum : an international quarterly journal · 2025Article
- Identification ofVeterinary sciences · 2024Article
- Trichinellosis dissemination among wild carnivores in the Republic of Kazakhstan: A 10-year study.Veterinary world · 2023Article
- Immunoproteomic Analysis ofPathogens (Basel, Switzerland) · 2022Article
- Hematological, biochemical, and serological parameters of experimentally infected rabbits withVeterinary world · 2022Article
- Serological testing forFood and waterborne parasitology · 2022Article
- Epidemiological perspective associated with principal risk factors ofVeterinary world · 2022Article
- Selected Livestock-Associated Zoonoses as a Growing Challenge for Public Health.Infectious disease reports · 2022Review
- A review of testing and assurance methods forFood and waterborne parasitology · 2021Article
- Animal welfare and zoonosis risk: anti-Trichinella antibodies in breeding pigs farmed under controlled housing conditions.Parasites & vectors · 2021Article
- Second outbreak of Trichinella pseudospiralis in Europe: clinical patterns, epidemiological investigation and identification of the etiological agent based on the western blot patterns of the patients' serum.Zoonoses and public health · 2021Article
- Differences in larval survival and IgG response patterns in long-lasting infections by Trichinella spiralis, Trichinella britovi and Trichinella pseudospiralis in pigs.Parasites & vectors · 2020Article
- Effects of TLR agonists on immune responses in Trichinella spiralis infected mice.Parasitology research · 2020Article
- Comparative Proteomic Analysis of Serum from Pigs Experimentally Infected withPathogens (Basel, Switzerland) · 2020Article
- Article
- Accreditation Procedure forFoods (Basel, Switzerland) · 2019Article
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6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundTrichinellosis is a meat-borne zoonotic disease caused by parasites of the genus Trichinella. To date, 12 taxa have been described. The identification of Trichinella species is crucial in order to identify the possible source of infection, the geographical origin of the parasite and to assess risk of infection for domestic pigs and humans. Specific identification of the etiological agent is not always feasible using direct methods since the source of infection can be untraceable. The aim of this study was to develop a diagnostic tool to infer the causative Trichinella species using western blot patterns of sera derived from infected animal and human hosts.
methodsSera from mice experimentally infected with Trichinella spiralis, Trichinella britovi, Trichinella pseudospiralis and Trichinella papuae were tested by western blot using homologous and heterologous crude worm extracts (CWE) and a highly sensitive detection system based on chemiluminescence. In addition, sera from pigs experimentally infected with T. spiralis, T. britovi and T. pseudospiralis and from patients with confirmed T. spiralis, T. britovi and T. pseudospiralis infections, were also included.
resultsSera from mice infected with one Trichinella species reacted with CWE proteins from all four investigated species. Likewise, sera derived from pigs and humans infected with one Trichinella species reacted with CWE proteins from all the three investigated species. Using T. spiralis CWE, sera from T. pseudospiralis-infected hosts yielded a characteristic pattern of reactivity using Wb, which differed to that produced by T. spiralis/T. britovi- or T. papuae-infected host sera.
conclusionsThe present study suggests that western blot using T. spiralis CWE may be a useful tool to distinguish Trichinella infections caused by T. pseudospiralis from those caused by T. spiralis or T. britovi. This method may support epidemiological investigations, particularly when the source of infection is not traceable.
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