ArticleEnvironmental health : a global access science source2018
The pulmonary and autonomic effects of high-intensity and low-intensity exercise in diesel exhaust.
Article in Environmental health : a global access science source, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Effects of controlled, acute exposure to air pollutants on heart rate variability in humans: a meta-regression and methodological recommendations.BMC public health · 2026Pooled it
- Effects of the inhaled dose of air pollution on health: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- The Acute Effects of Exercising in Air Pollution: A Systematic Review of Randomized Controlled Trials.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Examining the effect of salbutamol use in ozone air pollution by people with exercise-induced bronchoconstriction.Physiological reports · 2024Trial
- Pulmonary and cardiovascular responses to repeated ozone exposure during exercise in adults with exercise-induced bronchoconstriction.Physiological reports · 2026Article
- Air Pollution and Endurance Exercise: A Systematic Review of the Potential Effects on Cardiopulmonary Health.Life (Basel, Switzerland) · 2025Review
- Effects of physical exercise on cardio-respiratory health of young adults during short-term exposure to varying air pollution levels.BMC public health · 2024Article
- Controlled human exposures: a review and comparison of the health effects of diesel exhaust and wood smoke.Particle and fibre toxicology · 2024Review
- Physiological impacts of atmospheric pollution: Effects of environmental air pollution on exercise.Physiological reports · 2024Review
- Underground emissions and miners' personal exposure to diesel and renewable diesel exhaust in a Swedish iron ore mine.International archives of occupational and environmental health · 2022Article
- Controlled human exposure to diesel exhaust: a method for understanding health effects of traffic-related air pollution.Particle and fibre toxicology · 2022Review
- Controlled human exposure to diesel exhaust: results illuminate health effects of traffic-related air pollution and inform future directions.Particle and fibre toxicology · 2022Review
- HSP70 as a biomarker of the thin threshold between benefit and injury due to physical exercise when exposed to air pollution.Cell stress & chaperones · 2021Review
- The Diamond League athletic series: does the air quality sparkle?International journal of biometeorology · 2021Article
- Interaction between Long-Term Exposure to Fine Particulate Matter and Physical Activity, and Risk of Cardiovascular Disease and Overall Mortality in U.S. Women.Environmental health perspectives · 2020Article
- Low levels of fine particulate matter increase vascular damage and reduce pulmonary function in young healthy adults.Particle and fibre toxicology · 2020Article
- Acute effects of short-term exposure to air pollution while being physically active, the potential for modification: A review of the literature.Preventive medicine · 2020Review
- Respiratory Effects of Exposure to Traffic-Related Air Pollutants During Exercise.Frontiers in public health · 2020Review
- Article
- Effects of low-intensity and high-intensity cycling with diesel exhaust exposure on soluble P-selectin, E-selectin, I-CAM-1, VCAM-1 and complete blood count.BMJ open sport & exercise medicine · 2019Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExposure to air pollution impairs aspects of pulmonary and autonomic function and causes pulmonary inflammation. However, how exercising in air pollution affects these indices is poorly understood. Therefore, the purpose of this study was to determine the effects of low-intensity and high-intensity cycling with diesel exhaust (DE) exposure on pulmonary function, heart rate variability (HRV), fraction of exhaled nitric oxide (FeNO), norepinephrine and symptoms.
methodsEighteen males performed 30-min trials of low-intensity or high-intensity cycling (30 and 60% of power at VO
resultsThroat and chest symptoms were significantly greater immediately following DE exposure than following FA (p < 0.05). FeNO significantly increased 1 h following high-intensity exercise in DE (21.9 (2.4) vs. 19.3 (2.2) ppb) and FA (22.7 (1.7) vs. 19.9 (1.4)); however, there were no differences between the exposure conditions. All HRV indices significantly decreased following high-intensity exercise (p < 0.05) in DE and FA. The exception to this pattern was LF (nu) and LF/HF ratio, which significantly increased following high-intensity exercise (p < 0.05). Plasma norepinephrine (NE) significantly increased following high-intensity exercise in DE and FA, and this increase was greater than following rest and low-intensity exercise (p < 0.05). DE exposure did not modify any effects of exercise intensity on HRV or norepinephrine.
conclusionsHealthy individuals may not experience greater acute pulmonary and autonomic effects from exercising in DE compared to FA; therefore, it is unclear if such individuals will benefit from reducing vigorous activity on days with high concentrations on particulate matter.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.