Evidence map›Paper›PMID 30541346›Full record

Trial reportDiabetes & vascular disease research2019

Unsupervised high-intensity interval training improves glycaemic control but not cardiovascular autonomic function in type 2 diabetes patients: A randomised controlled trial.

Sophie Cassidy, Vivek Vaidya, David Houghton, Pawel Zalewski, Jelena P Seferovic, Kate Hallsworth, Guy A MacGowan, Michael I Trenell, Djordje G Jakovljevic

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Diabetes & vascular disease research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 5 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 5 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. The effects of aerobic exercise combined with resistance training on inflammatory factors and heart rate variability in middle-aged and elderly women with type 2 diabetes mellitus.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022
    Trial
  7. Trial
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Sophie Cassidy1 Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0002-0228-7274
Vivek Vaidya1 Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
David Houghton1 Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
Pawel Zalewski2 Department of Epidemiology, Faculty of Medicine, Nicolaus Copernicus University, Torun, Poland.
Jelena P Seferovic3 Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Kate Hallsworth1 Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
Guy A MacGowan1 Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
Michael I Trenell5 NIHR Innovation Observatory, Newcastle University, Newcastle Upon Tyne, UK.
Djordje G Jakovljevic1 Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
Newcastle University · GBBrigham and Women's Hospital · USNicolaus Copernicus University · PL

Funding

Department of Health SRF-2011-04-017Medical Research Council G0700718Medical Research Council MR/L016354/1
6 · The paper itself

Abstract

backgroundThis is the first randomised controlled trial to assess the impact of unsupervised high-intensity interval training on cardiovascular autonomic function in adults with type 2 diabetes.

methodsA total of 22 individuals with type 2 diabetes (age 60 ± 2 years, 17 males) lay in a supine position for 20 min for evaluation of cardiovascular autonomic function, which included (1) time domain measures of heart rate variability, (2) frequency domain measures of heart rate variability and blood pressure variability and (3) baroreflex receptor sensitivity. Participants were randomised into 12 weeks of high-intensity interval training (3 sessions/week) or standard care control group.

resultsAfter 12 weeks, the between-group change in HbA

conclusionHigh-intensity interval training improves glycaemic control but has limited effect on cardiovascular autonomic regulation in patients with type 2 diabetes.

Indexed as

High-Intensity Interval TrainingAutonomic Nervous SystemBaroreflexBiomarkersBlood GlucoseBlood PressureCardiovascular SystemDiabetes Mellitus, Type 2Diabetic NeuropathiesEnglandFemaleGlycated HemoglobinHeart RateHumansMaleMiddle AgedBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humancardiovascular diseasesExercisetype 2 diabetes mellitus

Identifiers

PMID30541346
PMCPMC6327303
OpenAlexW2905328123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.