Evidence map›Paper›PMID 30540947›Full record

ArticleCell reports2018

Condition-Dependent Neural Dimensions Progressively Shift during Reach to Grasp.

Adam G Rouse, Marc H Schieber

Abstract read
In one paragraph

Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Motor cortex flexibly deploys a high-dimensional repertoire of subskills.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. The neural mechanisms of manual dexterity.Nature reviews. Neuroscience · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adam G RouseDepartment of Neuroscience, University of Rochester, Rochester, NY 14642, USA; Del Monte Institute for Neuroscience, University of Rochester, Rochester, NY 14642, USA.
Marc H SchieberDepartment of Neuroscience, University of Rochester, Rochester, NY 14642, USA; Department of Neurology, University of Rochester, Rochester, NY 14642, USA; Department of Biomedical Engineering, University of Rochester, Rochester, NY 14642, USA; Del Monte Institute for Neuroscience, University of Rochester, Rochester, NY 14642, USA. Electronic address: mschiebe@ur.rochester.edu.

Funding

Observation of PerformanceR01NS102343 · NINDS · UNIVERSITY OF ROCHESTER · PI SCHIEBER, MARC H · 2018 to 2022
$2.5M
Reach, Grasp, and ManipulationR01NS079664 · NINDS · UNIVERSITY OF ROCHESTER · PI SCHIEBER, MARC H · 2012 to 2016
$1.7M
Neural encoding of motor precision for advancing brain-machine interfacesK99NS101127 · NINDS · UNIVERSITY OF ROCHESTER · PI ROUSE, ADAM G · 2017 to 2018
$175k
NINDS NIH HHS K99 NS101127NINDS NIH HHS R01 NS079664NINDS NIH HHS R01 NS102343
6 · The paper itself

Abstract

Neural population space analysis was performed to assess the dimensionality and dynamics of the neural population in the primary motor cortex (M1) during a reach-grasp-manipulation task in which both the reach location and the object being grasped were varied. We partitioned neural activity into three components: (1) general task-related activity independent of location and object, (2) location- and/or object-related activity, and (3) noise. Neural modulation related to location and/or object was only one-third the size of either general task modulation or noise. The neural dimensions of location and/or object-related activity overlapped with both the general task and noise dimensions. Rather than large amplitude modulation in a fixed set of dimensions, the active dimensions of location and/or object modulation shifted progressively over the time course of a trial.

Indexed as

Action PotentialsAnimalsBehavior, AnimalHand StrengthMacaca mulattaMotor ActivityNeuronsPrincipal Component AnalysisTask Performance and AnalysisTime Factorsdemixed PCAdimensionality reductiongraspingmanipulationneural populationneural variabilitypopulation dynamicsprimary motor cortexreachingstate space

Identifiers

PMID30540947
PMCPMC6361546

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.