Evidence map›Paper›PMID 30540251›Full record

ArticleeLife2018

Reactive oxygen species regulate activity-dependent neuronal plasticity in

Matthew Cw Oswald, Paul S Brooks, Maarten F Zwart, Amrita Mukherjee, Ryan Jh West, Carlo Ng Giachello, Khomgrit Morarach, Richard A Baines, Sean T Sweeney, Matthias Landgraf

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 117 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. GSK-3β coordinates axonal microtubule organization through Shot and Tau.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Effect of Warfarin on Lifespan and Oxidative Stress Tolerance ofInternational journal of molecular sciences · 2025
    Article
  16. Article
  17. Astrocyte-to-neuron HNature metabolism · 2025
    Article
  18. Article
  19. Glial Regulation of Circuit Wiring, Firing, and Expiring in theCold Spring Harbor perspectives in biology · 2024
    Review
  20. tRNA modification enzyme-dependent redox homeostasis regulates synapse formation and memory.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Matthew Cw OswaldDepartment of Zoology, University of Cambridge, Cambridge, United Kingdom.ORCID http://orcid.org/0000-0001-8586-9351
Paul S BrooksDepartment of Zoology, University of Cambridge, Cambridge, United Kingdom.
Maarten F ZwartHHMI Janelia Research Campus, Ashburn, United States.
Amrita MukherjeeDepartment of Zoology, University of Cambridge, Cambridge, United Kingdom.
Ryan Jh WestFaculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.ORCID https://orcid.org/0000-0001-9873-2258
Carlo Ng GiachelloFaculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Khomgrit MorarachDepartment of Zoology, University of Cambridge, Cambridge, United Kingdom.
Richard A BainesFaculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.ORCID https://orcid.org/0000-0001-8571-4376
Sean T Sweeney *Department of Biology, University of York, York, United Kingdom.
Matthias Landgraf *Department of Zoology, University of Cambridge, Cambridge, United Kingdom.ORCID http://orcid.org/0000-0001-5142-1997
University of Cambridge · GBUniversity of Manchester · GBJanelia Research Campus · USUniversity of York · GB

Funding

Biotechnology and Biological Sciences Research Council BB/I01179X/1Biotechnology and Biological Sciences Research Council BB/I012273/1Biotechnology and Biological Sciences Research Council BB/IO1179X/1Biotechnology and Biological Sciences Research Council BB/M002322/1Biotechnology and Biological Sciences Research Council BB/M002934/1Biotechnology and Biological Sciences Research Council BB/N/014561/1
6 · The paper itself

Abstract

Reactive oxygen species (ROS) have been extensively studied as damaging agents associated with ageing and neurodegenerative conditions. Their role in the nervous system under non-pathological conditions has remained poorly understood. Working with the

Indexed as

Neuronal PlasticityAnimalsAnimals, Genetically ModifiedDrosophila melanogasterDrosophila ProteinsLarvaMicroscopy, Electron, TransmissionMotor NeuronsNerve Tissue ProteinsNeuromuscular JunctionPhosphatidylinositol 3-KinasesPresynaptic TerminalsProtein Deglycase DJ-1PTEN PhosphohydrolaseReactive Oxygen SpeciesSignal TransductionDJ-1beta protein, DrosophilaDrosophila ProteinsNerve Tissue ProteinsPhosphatidylinositol 3-KinasesProtein Deglycase DJ-1PTEN PhosphohydrolaseReactive Oxygen SpeciesDJ-1D. melanogasterDrosophilaneuronneuroscienceplasticityROS (reactive oxygen species)synapse

Identifiers

PMID30540251
PMCPMC6307858
OpenAlexW2905082999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.