Evidence map›Paper›PMID 30540235›Full record

ReviewPhysiology (Bethesda, Md.)2019

Regulation of Ribosome Biogenesis in Skeletal Muscle Hypertrophy.

Vandré Casagrande Figueiredo, John J McCarthy

Open access · bronzeAbstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 2 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 2 syntheses or guidelines pooled it, 142 citations in OpenAlex.

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  14. Active transport of tRNAs facilitates distributed protein synthesis.bioRxiv : the preprint server for biology · 2026
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Vandré Casagrande FigueiredoThe Center for Muscle Biology, College of Health Sciences, University of Kentucky , Lexington, Kentucky.ORCID 0000-0002-3012-7905
John J McCarthyThe Center for Muscle Biology, College of Health Sciences, University of Kentucky , Lexington, Kentucky.
University of Kentucky · US

Funding

The role of satellite cells in adult skeletal muscle growth and maintenanceR01AR060701 · NIAMS · UNIVERSITY OF KENTUCKY · PI MCCARTHY, JOHN JOSEPH, PETERSON, CHARLOTTE A. · 2010 to 2019
$3.3M
The effects of exercise on satellite cell dynamics during agingR01AG049806 · NIA · UNIVERSITY OF KENTUCKY · PI MCCARTHY, JOHN JOSEPH, PETERSON, CHARLOTTE A. · 2016 to 2020
$1.8M
NIAMS NIH HHS R01 AR060701NIA NIH HHS R01 AG049806
6 · The paper itself

Abstract

The ribosome is the enzymatic macromolecular machine responsible for protein synthesis. The rates of protein synthesis are primarily dependent on translational efficiency and capacity. Ribosome biogenesis has emerged as an important regulator of skeletal muscle growth and maintenance by altering the translational capacity of the cell. Here, we provide evidence to support a central role for ribosome biogenesis in skeletal muscle growth during postnatal development and in response to resistance exercise training. Furthermore, we discuss the cellular signaling pathways regulating ribosome biogenesis, discuss how myonuclear accretion affects translational capacity, and explore future areas of investigation within the field.

Indexed as

AnimalsHumansHypertrophyMuscle DevelopmentMuscle, SkeletalProtein BiosynthesisResistance TrainingRibosomesSignal Transduction

Identifiers

PMID30540235
PMCPMC6383632
OpenAlexW2903863947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.