ArticleJournal of applied oral science : revista FOB2018
Inhibitory effect of reduced graphene oxide-silver nanocomposite on progression of artificial enamel caries.
Article in Journal of applied oral science : revista FOB, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Caries Management with Non-Metallic Nanomaterials: A Systematic Review.International journal of nanomedicine · 2022Pooled it
- Synthesis and Application of Silver Nanoparticles for Caries Management: A Review.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Graphene as a promising material in orthodontics: A review.Journal of orthodontic science · 2024Review
- The anti-adherence activity and bactericidal effect of GO against Streptococcus mutans from Iraqi dental patients.Odontology · 2023Article
- Can Graphene Pave the Way to Successful Periodontal and Dental Prosthetic Treatments? A Narrative Review.Biomedicines · 2023Review
- Implications of graphene-based materials in dentistry: present and future.Frontiers in chemistry · 2023Review
- In Vitro Studies of Graphene for Management of Dental Caries and Periodontal Disease: A Concise Review.Pharmaceutics · 2022Review
- Bionanocomposites in Caries Prevention and Treatment: A Systematic Review.Journal of pharmacy & bioallied sciences · 2022Review
- Research on Graphene and Its Derivatives in Oral Disease Treatment.International journal of molecular sciences · 2022Review
- Influence of the Physical Inclusion of ZrOBioMed research international · 2022Article
- Graphene-Based Nanomaterials for Dental Applications: Principles, Current Advances, and Future Outlook.Frontiers in bioengineering and biotechnology · 2022Review
- Article
- Effect of nanoparticle based intra-canal medicaments on root dentin micro-hardness.Bioinformation · 2022Article
- Metal and Metal Oxide Nanoparticles in Caries Prevention: A Review.Nanomaterials (Basel, Switzerland) · 2021Review
- Applications of Silver Nanoparticles in Dentistry: Advances and Technological Innovation.International journal of molecular sciences · 2021Review
- Evaluation of Synergic Potential of rGO/SiOPolymers · 2020Article
- Advances of Anti-Caries Nanomaterials.Molecules (Basel, Switzerland) · 2020Review
- Nanomaterials in Dentistry: State of the Art and Future Challenges.Nanomaterials (Basel, Switzerland) · 2020Review
- Use of Silver Nanomaterials for Caries Prevention: A Concise Review.International journal of nanomedicine · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe use of antimicrobial agents is an efficient method to prevent dental caries. Also, nanometric antibacterial agents with wide antibacterial spectrum and strong antibacterial effects can be applied for prevention of dental caries. The aim of this study was to evaluate the inhibitory effect of reduced graphene oxide-silver nanoparticles (rGO/Ag) composite on the progression of artificial enamel caries in a Streptococcus mutans biofilm model. MATERIAL AND
methodsEnamel specimens from bovine incisors were divided into eight treatment groups (n = 13), as follows: group 1 was inoculated with S. mutans grown in Brain Heart Infusion containing 1% sucrose (1% BHIS), as negative control; groups 2-4 were inoculated with S. mutans grown in the presence of different rGO/Ag concentrations (0.08, 0.12, 0.16 mg/mL) + 1% BHIS; group 5-7 were inoculated with S. mutans grown in the presence of different agents (0.16 mg/mL reduced graphene oxide, 0.16 mg/mL silver nanoparticles, 10 ppm NaF) + 1% BHIS; group 8 was mixed with 1% BHIS, without inoculation. Artificial enamel carious lesions were produced by S. mutans biofilm model for 7 days. Confocal laser scanning microscopy and atomic force microscopy were used to analyze roughness and morphology of the enamel surface. Polarized light microscopy and confocal laser scanning microscopy were employed to measure the lesion depth and the relative optical density (ROD) of the demineralized layer.
resultsCompared with the control groups, the rGO/Ag groups showed: (a) reduced enamel surface roughness; (b) much smoother and less eroded surfaces; (c) shallower lesion depth and less mineral loss.
conclusionAs a novel composite material, rGO/Ag can be a promising antibacterial agent for caries prevention.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.