Evidence map›Paper›PMID 30539977›Full record

Observational studyArquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery2018

IMPACT OF BARIATRIC SURGERY ON THE INFLAMMATORY STATE BASED ON CPR VALUE.

Renato Migliore, João Kleber Almeida Gentile, Fabiana Tornincasa Franca, Guilherme Tommasi Kappaz, Pedro Marcos Santinho Bueno-DE-Souza, José Cesar Assef

Open access · diamondAbstract readObservational Study
In one paragraph

Observational study in Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. WEIGHT LOSS COMPARISON AFTER SLEEVE AND ROUX-EN-Y GASTRIC BYPASS: SYSTEMATIC REVIEW.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2019
    Pooled it
  2. C-reactive protein and digestive pathologies: A narrative review for daily clinical use.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025
    Review
  3. Article
  4. Article
  5. Change in C-reactive protein after Roux-en-Y gastric bypass through 7 years of follow-up.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Renato MiglioreHospital of the Municipal Public Server, Technical Section of Digestive System Surgery, São Paulo, SP, Brazil.
João Kleber Almeida GentileHospital of the Municipal Public Server, Technical Section of Digestive System Surgery, São Paulo, SP, Brazil.
Fabiana Tornincasa FrancaHospital of the Municipal Public Server, Technical Section of Digestive System Surgery, São Paulo, SP, Brazil.
Guilherme Tommasi KappazHospital of the Municipal Public Server, Technical Section of Digestive System Surgery, São Paulo, SP, Brazil.
Pedro Marcos Santinho Bueno-DE-SouzaHospital of the Municipal Public Server, Technical Section of Digestive System Surgery, São Paulo, SP, Brazil.
José Cesar AssefHospital of the Municipal Public Server, Technical Section of Digestive System Surgery, São Paulo, SP, Brazil.
Hospital do Servidor Público Municipal · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPCR (C-reactive protein), produced in the liver after stimuli of inflammatory mediators, is determined as a marker of inflammatory activity (adipocytokines) and is present within adipocyte cells; besides being an inflammatory product, many studies have shown to be a predictor of complications.

aimTo determine if the inflammatory state of the obese patient decreases after bariatric surgery, based on pre and post-operative PCR.

methodsA prospective, observational study in patients undergoing Roux-en-Y gastric by-pass surgery followed up for three months after surgery, with serum preoperative CRP in 30, 60 and 90 days after surgery.

resultsA total of 19 patients, who had a mean CRP value before the surgical procedure of 0.80(±0.54) mg/dl, were followed, and when compared to the CRP with 30 days of surgery, they presented a significant increase to 2.68 mg/dl (p=0.012). When compared with the PCR of 60 days after the surgical procedure, it was also higher with the value of 3.32 mg/dl (p=0.27). However, at three months after surgery, the CRP showed a decrease when compared to the preoperative mark, with value of 0.45 mg/dl (p=0.0042).

conclusionRoux-en-Y gastric bypass was able to decrease the chronic inflammation status of these patients, based on the value of CRP, with three months of surgery.

Indexed as

AdultChronic DiseaseC-Reactive ProteinFemaleGastric BypassHumansInflammationMaleMiddle AgedObesityPostoperative PeriodPreoperative PeriodProspective StudiesReference ValuesTime FactorsTreatment OutcomeC-Reactive Protein

Identifiers

PMID30539977
PMCPMC6284396
OpenAlexW2904990128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.